| PDB ID | 1VCB
|
CHAIN | B |
|---|---|---|---|
| Protein name | PROTEIN (ELONGIN C) | ||
| Uniprot Accession | Q15369 | ||
| The number of similar proteins | 125 | ||
| The number of binding states | 17 | ||
| The number of binding partners | 14 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1VCB (CHAIN: B) | |
| 1 |
Q15370
P40337
|
| 2 |
Q15370
Q9Y2U9
|
| 3 |
Q15370
2IZV
|
| 4 |
Q15370
P12504
|
| 5 |
Q15370
Q96DX5
|
| 6 |
P62869
Q7KRQ1
|
| 7 |
Q15370
O35718
|
| 8 |
Q15370
E1ANT9
Q13951
|
| 9 |
Q15370
Q9Y2U9
Q9Y2U9
|
| 10 |
Q15370
P40337
Q13617
|
| 11 |
Q15370
Q15370
P40337
|
| 12 |
Q15370
P40337
P40337
|
| 13 |
Q15370
P40337
Q16665
|
| 14 |
Q15370
P40337
Q13617
|
| 15 |
P62869
O14508
Q93034
|
| 16 |
Q15370
Q15370
P40337
P40337
|
| 17 |
Q15370
Q72499
Q13951
Q93034
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 79_TYR | SER |
ClinVar chr8:74858968 rs1057519973 |
Likely pathogenic | - | 0.9925 | Papillary renal cell carcinoma type 1 [Human Phenotype Ontology:HP:0011797,MedGen:C1336839,OMIM:605074,Orphanet:47044] | |
| 79_TYR | ASN |
ClinVar chr8:74858969 rs1057519974 |
Likely pathogenic | - | 0.9941 | Papillary renal cell carcinoma type 1 [Human Phenotype Ontology:HP:0011797,MedGen:C1336839,OMIM:605074,Orphanet:47044] | |
| 79_TYR | PHE |
ClinVar chr8:74858968 rs1057519973 |
Likely pathogenic | - | 0.689 | Papillary renal cell carcinoma type 1 [Human Phenotype Ontology:HP:0011797,MedGen:C1336839,OMIM:605074,Orphanet:47044] | |
| 82_ARG | GLY |
8.3kJPN chr8:74858960 - |
- | 0.0001 | 0.9827 | - |