PDB ID 1KTZ     CHAIN B
Protein name TGF-beta Type II Receptor
Uniprot Accession P37173
The number of similar proteins 12
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1KTZ (CHAIN: B)
1 P10600  
2 Monomeric state
3 A0A2P1IQ80  
4 8G4K  
5 P36897   P01137  

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Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   VTDNNGAVKF   PQLCKFCDVR   FSTCDNQKSC   MSNCSITSIC   EKPQEVCVAV   50
51   WRKNDENITL   ETVCHDPKLP   YHDFILEDAA   SPKCIMKEKK   KPGETFFMCS   100
101   CSSDECNDNI   IFSEEYNTSN   PD       150

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
38_CYS ARG VAR_041414
-
US - 0.9969 A gastric adenocarcinoma sample
50_ILE VAL VAR_036070
-
US - 0.1239 A colorectal cancer sample
67_LYS GLN 8.3kJPN
chr3:30691766
-
- 0.0001 0.1315 -
87_ASP TYR 8.3kJPN
chr3:30691826
-
- 0.0001 0.2829 -
114_SER PHE 8.3kJPN
chr3:30691908
-
- 0.0001 0.6932 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.