PDB ID 1IZN     CHAIN B
Protein name CapZ beta-1 subunit
Uniprot Accession P14315
The number of similar proteins 20
The number of binding states 7
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1IZN (CHAIN: B)
1 P13127  
2 P13127   Q6EDY6  
3 P13127   Q6EDY6  
4 P62774   P13127  
5 Q91YR1   P13127  
6 Q91YR1   P58546   P13127  
7 Q12792   Q5RKN9   P68135   P68135  

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Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MSDQQLDCAL   DLMRRLPPQQ   IEKNLSDLID   LVPSLCEDLL   SSVDQPLKIA   50
51   RDKVVGKDYL   LCDYNRDGDS   YRSPWSNKYD   PPLEDGAMPS   ARLRKLEVEA   100
101   NNAFDQYRDL   YFEGGVSSVY   LWDLDHGFAG   VILIKKAGDG   SKKIKGCWDS   150
151   IHVVEVQEKS   SGRTAHYKLT   STVMLWLQTN   KTGSGTMNLG   GSLTRQMEKD   200
201   ETVSDSSPHI   ANIGRLVEDM   ENKIRSTLNE   IYFGKTKDIV   NGLRSIDAIP   250
251   DNQKYKQLQR   ELSQVLTQRQ   IYIQPDN       300

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
23_LYS THR gnomAD
chr1:19746180
rs185128330
- 0.000242572 - -
23_LYS THR 8.3kJPN
chr1:19746180
rs185128330
- 0.0003 - -
55_VAL MET 8.3kJPN
chr1:19712051
rs1457096979
- 0.0001 - -
210_ILE VAL 8.3kJPN
chr1:19671707
-
- 0.0001 - -
241_ASN SER gnomAD
chr1:19670861
rs181908306
- 0.00179134 - -
241_ASN THR 8.3kJPN
chr1:19670861
rs181908306
- - - -
256_LYS ASN 8.3kJPN
chr1:19669322
-
- 0.0001 - -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.