| PDB ID | 1GG2
|
CHAIN | B |
|---|---|---|---|
| Protein name | G PROTEIN GI BETA 1 | ||
| Uniprot Accession | P62871 | ||
| The number of similar proteins | 56 | ||
| The number of binding states | 11 | ||
| The number of binding partners | 9 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1GG2 (CHAIN: B) | |
| 1 |
P63212
P63096
|
| 2 |
P63212
|
| 3 |
P63212
P21146
|
| 4 |
P59768
Q8C4T8
|
| 5 |
P02698
P20942
|
| 6 |
P02698
6B20
|
| 7 |
P04901
P04901
P02698
|
| 8 |
P59768
P63096
6CRK
|
| 9 |
P59768
P63092
D9IEF7
7JOZ
|
| 10 |
P62873
P62873
P59768
Q96CX2
Q96CX2
|
| 11 |
P62873
P62873
P59768
Q96CX2
Q96CX2
Q96CX2
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 3_GLU | LYS |
8.3kJPN chr3:179143982 rs955229785 |
- | 0.0001 | - | - | |
| 8_ARG | HIS |
8.3kJPN chr12:6950474 rs199531660 |
- | 0.0004 | - | - | |
| 11_ALA | VAL |
8.3kJPN chr12:6950483 rs782550076 |
- | 0.0001 | - | - | |
| 19_ARG | GLN |
8.3kJPN chr7:100273944 - |
- | 0.0001 | - | - | |
| 21_ALA | VAL |
8.3kJPN chr7:100274162 - |
- | 0.0001 | - | - | |
| 22_ARG | GLN |
8.3kJPN chr3:179138708 rs1318528118 |
- | 0.0001 | - | - | |
| 24_ALA | VAL |
8.3kJPN chr12:6950763 - |
- | 0.0001 | - | - | |
| 29_THR | ALA |
8.3kJPN chr1:1749287 rs758197716 |
- | 0.0001 | - | - | |
| 29_THR | MET |
8.3kJPN chr3:179138687 rs762114369 |
- | 0.0002 | - | - | |
| 30_LEU | VAL |
8.3kJPN chr12:6950780 rs1429928202 |
- | 0.0001 | - | - | |
| 31_THR | SER |
8.3kJPN chr7:100274192 - |
- | 0.0002 | - | - | |
| 37_ILE | MET |
gnomAD chr1:1747287 rs754777749 |
- | 0.000151198 | - | - | |
| 43_ILE | MET |
8.3kJPN chr3:179137261 rs1187523844 |
- | 0.0002 | - | - | |
| 47_THR | MET |
gnomAD chr12:6952177 rs116400596 |
- | 0.000141787 | - | - | |
| 47_THR | MET |
8.3kJPN chr12:6952177 rs116400596 |
- | 0.0001 | - | - | |
| 49_ARG | GLN |
8.3kJPN chr12:6952183 rs782393502 |
- | 0.0001 | - | - | |
| 57_LYS | GLU |
8.3kJPN chr1:1747229 rs141326438 |
- | 0.0002 | - | - | |
| 59_TYR | ASP |
8.3kJPN chr12:6952212 - |
- | 0.0001 | - | - | |
| 60_ALA | THR |
8.3kJPN chr12:6952215 rs782554195 |
- | 0.0001 | - | - | |
| 63_TRP | CYS |
8.3kJPN chr7:100274408 - |
- | 0.0001 | - | - | |
| 66_ASP | HIS |
8.3kJPN chr7:100274415 - |
- | 0.0001 | - | - | |
| 76_ASP | TYR |
8.3kJPN chr12:6952360 rs2234756 |
- | 0.0094 | - | - | |
| 81_VAL | MET |
8.3kJPN chr12:6952375 rs45616032 |
- | 0.0001 | - | - | |
| 87_THR | ALA |
gnomAD chr3:179134289 rs780046027 |
- | 0.000244076 | - | - | |
| 94_PRO | LEU |
8.3kJPN chr12:6952540 rs999189577 |
- | 0.0001 | - | - | |
| 106_ALA | THR |
8.3kJPN chr7:100275169 - |
- | 0.0001 | - | - | |
| 107_PRO | SER |
8.3kJPN chr3:179132784 - |
- | 0.0001 | - | - | |
| 108_SER | PHE |
8.3kJPN chr3:179132780 - |
- | 0.0003 | - | - | |
| 115_GLY | ARG |
8.3kJPN chr12:6952602 rs201963490 |
- | 0.0002 | - | - | |
| 123_ILE | VAL |
8.3kJPN chr12:6952626 rs782780703 |
- | 0.0001 | - | - | |
| 125_ASN | SER |
8.3kJPN chr1:1735914 rs150628410 |
- | 0.0002 | - | - | |
| 127_LYS | ARG |
8.3kJPN chr12:6952639 rs1555123844 |
- | 0.0005 | - | - | |
| 129_ARG | HIS |
8.3kJPN chr12:6952645 rs201797921 |
- | 0.0002 | - | - | |
| 133_VAL | MET |
8.3kJPN chr3:179132706 - |
- | 0.0001 | - | - | |
| 134_LYS | ARG |
gnomAD chr12:6952660 rs61747607 |
- | 0.000560783 | - | - | |
| 143_THR | ILE |
8.3kJPN chr3:179132675 - |
- | 0.0001 | - | - | |
| 175_GLN | HIS |
8.3kJPN chr7:100275748 rs1187109793 |
- | 0.0002 | - | - | |
| 177_THR | ASN |
8.3kJPN chr3:179131369 rs1274879698 |
- | 0.0003 | - | - | |
| 178_THR | ILE |
8.3kJPN chr12:6952976 - |
- | 0.0001 | - | - | |
| 187_VAL | ALA |
8.3kJPN chr7:100275783 - |
- | 0.0001 | - | - | |
| 195_ASP | ASN |
gnomAD chr7:100275806 rs79631023 |
- | 0.000751575 | - | - | |
| 200_VAL | LEU |
8.3kJPN chr7:100275821 - |
- | 0.0001 | - | - | |
| 208_ILE | VAL |
8.3kJPN chr7:100275845 rs752126417 |
- | 0.0003 | - | - | |
| 214_ARG | TER |
8.3kJPN chr12:6953083 rs367934996 |
- | 0.0001 | - | - | |
| 219_ARG | CYS |
8.3kJPN chr12:6953098 rs782266619 |
- | 0.0002 | - | - | |
| 220_GLN | ARG |
8.3kJPN chr3:179131240 rs199615251 |
- | 0.0001 | - | - | |
| 223_THR | MET |
gnomAD chr3:179131231 rs144385061 |
- | 0.000131316 | - | - | |
| 226_GLU | GLN |
gnomAD chr12:6953119 rs371744474 |
- | 0.000333483 | - | - | |
| 226_GLU | LYS |
8.3kJPN chr1:1721857 - |
- | 0.0001 | - | - | |
| 239_ASN | SER |
8.3kJPN chr1:1720692 rs760166038 |
- | 0.0001 | - | - | |
| 240_ALA | THR |
8.3kJPN chr7:100276039 - |
- | 0.0001 | - | - | |
| 245_SER | LEU |
8.3kJPN chr12:6954784 rs782597916 |
- | 0.0004 | - | - | |
| 251_ARG | HIS |
8.3kJPN chr12:6954802 rs782467023 |
- | 0.0001 | - | - | |
| 256_ARG | GLN |
8.3kJPN chr12:6954817 rs781879948 |
- | 0.0001 | - | - | |
| 267_GLU | LYS |
gnomAD chr12:6954849 rs150593798 |
- | 0.000139228 | - | - | |
| 267_ASP | ASN |
8.3kJPN chr3:179123095 rs752762550 |
- | 0.0001 | - | - | |
| 268_ASN | SER |
8.3kJPN chr1:1720605 rs757342463 |
- | 0.0002 | - | - | |
| 268_ASN | ILE |
8.3kJPN chr7:100276124 rs147810006 |
- | 0.0001 | - | - | |
| 268_SER | ARG |
8.3kJPN chr12:6954854 - |
- | 0.0003 | - | - | |
| 271_CYS | TYR |
8.3kJPN chr3:179123082 - |
- | 0.0001 | - | - | |
| 272_GLY | SER |
gnomAD chr12:6954864 rs5442 |
- | 0.0484364 | - | - | |
| 287_ALA | SER |
8.3kJPN chr12:6954909 rs782090563 |
- | 0.0001 | - | - | |
| 289_TYR | CYS |
8.3kJPN chr3:179123028 - |
- | 0.0001 | - | - | |
| 294_CYS | ARG |
8.3kJPN chr3:179123014 - |
- | 0.0001 | - | - | |
| 299_ALA | VAL |
8.3kJPN chr1:1720512 - |
- | 0.0001 | - | - | |
| 304_ARG | CYS |
8.3kJPN chr3:179122984 rs201776673 |
- | 0.0001 | - | - | |
| 309_ALA | THR |
8.3kJPN chr7:100276326 rs1554371972 |
- | 0.0001 | - | - | |
| 313_ASN | SER |
8.3kJPN chr3:179119086 - |
- | 0.0001 | - | - | |
| 320_VAL | ILE |
gnomAD chr3:179119066 rs61750380 |
- | 0.00419188 | - | - | |
| 330_GLY | ASP |
8.3kJPN chr12:6956028 - |
- | 0.0001 | - | - |