PDB ID 1GFW     CHAIN B
Protein name CASPASE-3 (APOPAIN, P10)
Uniprot Accession P42574
The number of similar proteins 96
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1GFW (CHAIN: B)
1 P42574  
2 P42574   2XZT  
3 P42574   P42574   P42574  
4 P42574   P42574   P42574   P98170   P98170  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   DMACHKIPVD   ADFLYAYSTA   PGYYSWRNSK   DGSWFIQSLC   AMLKQYADKL   50
51   EFMHILTRVN   RKVATEFESF   SFDATFHAKK   QIPCIVSMLT   KELYFYH   100

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
186_LYS ASN 8.3kJPN
chr4:185552237
-
- 0.0001 -
217_GLN HIS 8.3kJPN
chr4:185550609
rs754910045
- 0.0001 -
218_SER LEU gnomAD
chr4:185550607
rs371145290
- 0.000123411 -
222_MET ILE 8.3kJPN
chr4:185550594
-
- 0.0001 -
254_ALA THR 8.3kJPN
chr4:185550500
rs1393598499
- 0.0001 -
270_THR ARG 8.3kJPN
chr4:185550451
-
- 0.0001 -
277_HIS TYR gnomAD
chr4:185550431
rs147767351
- 0.000344055 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.