PDB ID 1E9H     CHAIN B
Protein name CYCLIN A3
Uniprot Accession P20248
The number of similar proteins 122
The number of binding states 5
The number of binding partners 3

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1E9H (CHAIN: B)
1 1E9H  
2 Monomeric state
3 P24941   P46527  
4 P24941   P24941  
5 P24941   Q99741  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   VPDYHEDIHT   YLREMEVKCK   PKVGYMKKQP   DITNSMRAIL   VDWLVEVGEE   50
51   YKLQNETLHL   AVNYIDRFLS   SMSVLRGKLQ   LVGTAAMLLA   SKFEEIYPPE   100
101   VAEFVYITDD   TYTKKQVLRM   EHLVLKVLTF   DLAAPTVNQF   LTQYFLHQQP   150
151   ANCKVESLAM   FLGELSLIDA   DPYLKYLPSV   IAGAAFHLAL   YTVTGQSWPE   200
201   SLIRKTGYTL   ESLKPCLMDL   HQTYLKAPQH   AQQSIREKYK   NSKYHGVSLL   250
251   NPPETLNLLN   L         300

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
180_GLU VAL gnomAD
chr4:122742165
rs147878070
- 0.00034219 0.148 -
327_CYS ARG 8.3kJPN
chr4:122740550
-
- 0.0001 0.0969 -
403_GLN HIS gnomAD
chr4:122739240
rs568350890
- 0.00024675 0.1236 -
422_SER PRO 8.3kJPN
chr4:122738828
-
- 0.0002 0.9731 -
427_PRO ARG 8.3kJPN
chr4:122738812
-
- 0.0001 0.5863 -
427_PRO THR 8.3kJPN
chr4:122738813
-
- 0.0001 0.3432 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.