PDB ID 1D5X     CHAIN B
Protein name HLA CLASS II HISTOCOMPATIBILITY ANTIGEN
Uniprot Accession P13760
The number of similar proteins 129
The number of binding states 20
The number of binding partners 11

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1D5X (CHAIN: B)
1 P01903  
2 P01903  
3 P01903   8EUQ  
4 P01903   4Y19  
5 P01903   P01730  
6 P01903   P28068  
7 6R0E   P01903  
8 P01903   Q48898  
9 P01903   O85383  
10 P01903   P03205  
11 P01903   RWHUAC   S18894  
12 P01903   3O6F   3O6F  
13 A2BFX2   P01903   P01903  
14 P04229   P01903   P01903  
15 RWHUAC   P01850   P01903  
16 29293741   P01850   P01903  
17 6CQL   6CQL   P01903  
18 4E41   4E41   P01903  
19 4H1L   P01903   4H1L  
20 P01903   3T0E   3T0E   P01730  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   GDTRPRFLEQ   VKHECHFFNG   TERVRFLDRY   FYHQEEYVRF   DSDVGEYRAV   50
51   TELGRPDAEY   WNSQKDLLEQ   KRAAVDTYCR   HNYGVGESFT   VQRRVYPEVT   100
101   VYPAKTQPLQ   HHNLLVCSVN   GFYPGSIEVR   WFRNGQEEKT   GVVSTGLIQN   150
151   GDWTFQTLVM   LETVPRSGEV   YTCQVEHPSL   TSPLTVEWRA   RS   200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
1_GLY ARG gnomAD
chr6:32497914 		rs76748970
- 0.239628 -
1_GLY VAL 8.3kJPN
chr6:32497913 		rs146966122
- 0.0927 -
1_GLY ARG 8.3kJPN
chr6:32497914 		rs76748970
- 0.3082 -
1_GLY VAL 8.3kJPN
chr6:32557431 		rs761074986
- 0.0696 -
2_ASP ASN gnomAD
chr6:32557429 		rs372634318
- 0.000413715 -
2_ASP GLY 8.3kJPN
chr6:32497910 		rs139583918
- 0.1119 -
2_ASP GLU 8.3kJPN
chr6:32557427 		-
- 0.0001 -
2_ASP GLY 8.3kJPN
chr6:32557428 		rs201700261
- 0.1078 -
3_THR PRO 8.3kJPN
chr6:32497908 		rs796754225
- 0.0031 -
3_THR PRO 8.3kJPN
chr6:32557426 		rs749376442
- 0.0011 -
4_ARG GLY gnomAD
chr6:32557423 		rs9256943
- 0.0522666 -
4_ARG GLN 8.3kJPN
chr6:32497904 		rs1141741
- 0.1696 -
4_ARG TER 8.3kJPN
chr6:32497905 		rs71549219
- - -
4_ARG GLN 8.3kJPN
chr6:32557422 		rs17879746
- 0.274 -
5_PRO SER 8.3kJPN
chr6:32557420 		rs761045049
- 0.0001 -
6_ARG CYS 8.3kJPN
chr6:32489949 		rs1136744
- 0.0124 -
9_GLN ARG gnomAD
chr6:32489939 		rs17433849
- 0.000101551 -
9_GLN GLU gnomAD
chr6:32489940 		rs1071747
- 0.0301896 -
9_GLN LYS gnomAD
chr6:32489940 		rs1071747
- 0.0801815 -
9_TRP GLY gnomAD
chr6:32552144 		rs9269959
- 0.0278498 -
9_GLN ARG 8.3kJPN
chr6:32489939 		rs17433849
- 0.0033 -
9_GLN TER 8.3kJPN
chr6:32489940 		rs1071747
- - -
9_TRP TER 8.3kJPN
chr6:32552143 		rs9269958
- 0.5107 -
9_TRP GLY 8.3kJPN
chr6:32552144 		rs9269959
- 0.4539 -
10_GLN LEU gnomAD
chr6:32489936 		rs201948867
- 0.00139793 -
10_GLN LEU gnomAD
chr6:32552140 		rs17882663
- 0.0184337 -
10_GLN LEU 8.3kJPN
chr6:32489936 		rs201948867
- 0.0661 -
10_GLN GLU 8.3kJPN
chr6:32489937 		rs200071340
- 0.0083 -
10_GLN LEU 8.3kJPN
chr6:32552140 		rs17882663
- 0.1363 -
11_ASP VAL gnomAD
chr6:32489933 		rs1071748
- 0.00220524 -
11_ASP GLY gnomAD
chr6:32489933 		rs1071748
- 0.000232851 -
11_ASP HIS gnomAD
chr6:32489934 		rs1136752
- 0.00218949 -
11_PRO LEU gnomAD
chr6:32552137 		rs17878703
- 0.0263411 -
11_PRO ARG gnomAD
chr6:32552137 		rs17878703
- 0.000573792 -
11_PRO ALA gnomAD
chr6:32552138 		rs9269955
- 0.00589531 -
11_ASP VAL 8.3kJPN
chr6:32489933 		rs1071748
- - -
11_ASP HIS 8.3kJPN
chr6:32489934 		rs1136752
- 0.0698 -
11_PRO LEU 8.3kJPN
chr6:32552137 		rs17878703
- - -
11_PRO SER 8.3kJPN
chr6:32552138 		rs9269955
- - -
12_LYS THR gnomAD
chr6:32489930 		rs200581589
- 0.0371716 -
12_LYS THR gnomAD
chr6:32552134 		rs1136756
- 0.186264 -
12_LYS THR 8.3kJPN
chr6:32489930 		rs200581589
- 0.0239 -
12_LYS THR 8.3kJPN
chr6:32552134 		rs1136756
- 0.293 -
12_LYS TER 8.3kJPN
chr6:32552135 		rs766505678
- 0.0011 -
13_TYR PHE gnomAD
chr6:32489927 		rs1136760
- 0.0732127 -
13_TYR SER gnomAD
chr6:32489927 		rs1136760
- 0.0473745 -
13_TYR HIS gnomAD
chr6:32489928 		rs1136757
- 0.000154771 -
13_ARG SER gnomAD
chr6:32552130 		rs9269951
- 0.293707 -
13_ARG MET gnomAD
chr6:32552131 		rs1136759
- 0.00891459 -
13_ARG THR gnomAD
chr6:32552131 		rs1136759
- 0.229957 -
13_ARG LYS gnomAD
chr6:32552131 		rs1136759
- 0.000120467 -
13_ARG TRP gnomAD
chr6:32552132 		rs1136758
- 0.247761 -
13_ARG GLY gnomAD
chr6:32552132 		rs1136758
- 0.0272216 -
13_TYR PHE 8.3kJPN
chr6:32489927 		rs1136760
- - -
13_TYR HIS 8.3kJPN
chr6:32489928 		rs1136757
- 0.2337 -
13_ARG SER 8.3kJPN
chr6:32552130 		rs9269951
- 0.7669 -
13_ARG MET 8.3kJPN
chr6:32552131 		rs1136759
- - -
13_ARG TRP 8.3kJPN
chr6:32552132 		rs1136758
- - -
14_GLU LYS 8.3kJPN
chr6:32489925 		rs17405212
- 0.0027 -
16_HIS TYR gnomAD
chr6:32489919 		rs199680107
- 0.0125183 -
16_HIS GLN gnomAD
chr6:32552121 		rs17879981
- 0.000590411 -
16_HIS TYR gnomAD
chr6:32552123 		rs17879702
- 0.031714 -
16_HIS TYR 8.3kJPN
chr6:32489919 		rs199680107
- 0.0061 -
16_HIS GLN 8.3kJPN
chr6:32552121 		rs17879981
- 0.0187 -
16_HIS TYR 8.3kJPN
chr6:32552123 		rs17879702
- 0.1645 -
18_PHE LEU gnomAD
chr6:32552117 		rs114435757
- 0.00153931 -
18_PHE LEU 8.3kJPN
chr6:32489913 		rs201628145
- 0.0676 -
18_PHE TYR 8.3kJPN
chr6:32552116 		-
- 0.0001 -
18_PHE LEU 8.3kJPN
chr6:32552117 		rs114435757
- 0.2573 -
22_GLU GLN 8.3kJPN
chr6:32552105 		-
- 0.0001 -
23_ARG LEU 8.3kJPN
chr6:32552101 		-
- 0.0001 -
24_VAL GLU 8.3kJPN
chr6:32552098 		rs1335931724
- 0.0008 -
25_ARG GLN gnomAD
chr6:32552095 		rs17885382
- 0.000191237 -
25_ARG GLN 8.3kJPN
chr6:32489891 		rs112906420
- 0.0012 -
25_ARG TRP 8.3kJPN
chr6:32489892 		rs184278615
- 0.0838 -
25_ARG GLN 8.3kJPN
chr6:32552095 		rs17885382
- 0.0014 -
25_ARG TRP 8.3kJPN
chr6:32552096 		rs188617679
- 0.2577 -
26_PHE LEU gnomAD
chr6:32489887 		rs202197820
- 0.000648374 -
26_PHE LEU gnomAD
chr6:32489887 		rs202197820
- 0.00119301 -
26_PHE TYR gnomAD
chr6:32489888 		rs147440497
- 0.0457758 -
26_PHE LEU gnomAD
chr6:32552091 		rs1059572
- 0.0106895 -
26_PHE TYR gnomAD
chr6:32552092 		rs1059569
- 0.131883 -
26_PHE ILE gnomAD
chr6:32552093 		rs201128876
- 0.00153433 -
26_PHE TYR 8.3kJPN
chr6:32489888 		rs147440497
- 0.3205 -
26_PHE ILE 8.3kJPN
chr6:32489889 		rs201469165
- 0.0856 -
26_PHE LEU 8.3kJPN
chr6:32552091 		rs1059572
- - -
26_PHE TYR 8.3kJPN
chr6:32552092 		rs1059569
- 0.3616 -
26_PHE ILE 8.3kJPN
chr6:32552093 		rs201128876
- 0.2045 -
28_HIS GLN gnomAD
chr6:32489881 		rs202185589
- 0.000211982 -
28_HIS GLN gnomAD
chr6:32489881 		rs202185589
- 0.00071544 -
28_HIS ASP gnomAD
chr6:32489883 		rs142793258
- 0.0371285 -
28_ASP GLU gnomAD
chr6:32552085 		rs1059575
- 0.0502833 -
28_ASP GLU gnomAD
chr6:32552085 		rs1059575
- 0.0718385 -
28_ASP VAL gnomAD
chr6:32552086 		rs200532329
- 0.00159896 -
28_ASP TYR gnomAD
chr6:32552087 		rs17878947
- 0.0505099 -
28_ASP ASN gnomAD
chr6:32552087 		rs17878947
- 0.00163787 -
28_HIS GLN 8.3kJPN
chr6:32489881 		rs202185589
- - -
28_HIS LEU 8.3kJPN
chr6:32489882 		rs200298678
- 0.0902 -
28_HIS TYR 8.3kJPN
chr6:32489883 		rs142793258
- - -
28_ASP GLU 8.3kJPN
chr6:32552085 		rs1059575
- - -
28_ASP VAL 8.3kJPN
chr6:32552086 		rs200532329
- 0.2569 -
28_ASP TYR 8.3kJPN
chr6:32552087 		rs17878947
- - -
30_ASP GLY gnomAD
chr6:32489876 		rs41546317
- 0.273379 -
30_ASP TYR gnomAD
chr6:32489877 		rs138849995
- 0.0248491 -
30_ASP HIS gnomAD
chr6:32489877 		rs138849995
- 0.000192949 -
30_TYR PHE gnomAD
chr6:32552080 		rs3175105
- 0.000143563 -
30_TYR CYS gnomAD
chr6:32552080 		rs3175105
- 0.0114161 -
30_TYR HIS gnomAD
chr6:32552081 		rs11554462
- 0.0164392 -
30_ASP VAL 8.3kJPN
chr6:32489876 		rs41546317
- - -
30_ASP TYR 8.3kJPN
chr6:32489877 		rs138849995
- - -
30_TYR PHE 8.3kJPN
chr6:32552080 		rs3175105
- - -
30_TYR HIS 8.3kJPN
chr6:32552081 		rs11554462
- 0.1285 -
31_ILE PHE gnomAD
chr6:32489874 		rs140781802
- 0.0253416 -
31_ILE VAL gnomAD
chr6:32489874 		rs140781802
- 0.000165271 -
31_PHE ILE gnomAD
chr6:32552078 		rs17882300
- 0.0234445 -
31_ILE PHE 8.3kJPN
chr6:32489874 		rs140781802
- - -
31_PHE ILE 8.3kJPN
chr6:32552078 		rs17882300
- - -
32_TYR HIS gnomAD
chr6:32489871 		rs137863146
- 0.0159466 -
32_TYR HIS gnomAD
chr6:32552075 		rs1064664
- 0.256396 -
32_TYR HIS 8.3kJPN
chr6:32489871 		rs137863146
- 0.0664 -
32_TYR HIS 8.3kJPN
chr6:32552075 		rs1064664
- 0.2465 -
33_ASN HIS gnomAD
chr6:32489868 		rs1059576
- 0.000671158 -
33_ASN HIS gnomAD
chr6:32552072 		rs17879995
- 0.115207 -
33_ASN HIS 8.3kJPN
chr6:32489868 		rs1059576
- 0.1914 -
33_ASN THR 8.3kJPN
chr6:32552071 		-
- 0.0001 -
33_ASN HIS 8.3kJPN
chr6:32552072 		rs17879995
- 0.1318 -
37_ASP VAL gnomAD
chr6:32489855 		rs200042906
- 0.00121985 -
37_ASP ALA gnomAD
chr6:32489855 		rs200042906
- 0.00592497 -
37_ASP TYR gnomAD
chr6:32489856 		rs707956
- 0.086144 -
37_ASP ASN gnomAD
chr6:32489856 		rs707956
- 0.262709 -
37_SER PHE gnomAD
chr6:32552059 		rs707957
- 0.0795254 -
37_SER TYR gnomAD
chr6:32552059 		rs707957
- 0.568406 -
37_SER THR gnomAD
chr6:32552060 		rs16822820
- 0.194034 -
37_ASP GLU 8.3kJPN
chr6:32489854 		rs770407170
- 0.0007 -
37_ASP VAL 8.3kJPN
chr6:32489855 		rs200042906
- - -
37_ASP TYR 8.3kJPN
chr6:32489856 		rs707956
- - -
37_SER PHE 8.3kJPN
chr6:32552059 		rs707957
- - -
37_SER THR 8.3kJPN
chr6:32552060 		rs16822820
- 0.0921 -
38_LEU SER gnomAD
chr6:32489852 		rs192498095
- 0.010882 -
38_LEU VAL gnomAD
chr6:32489853 		rs1059580
- 0.379601 -
38_VAL ALA gnomAD
chr6:32552056 		rs17878951
- 0.00251768 -
38_VAL LEU gnomAD
chr6:32552057 		rs17878614
- 0.00358455 -
38_LEU SER 8.3kJPN
chr6:32489852 		rs192498095
- 0.1272 -
38_VAL ALA 8.3kJPN
chr6:32552056 		rs17878951
- 0.3105 -
38_VAL LEU 8.3kJPN
chr6:32552057 		rs17878614
- 0.057 -
39_ARG GLY 8.3kJPN
chr6:32552054 		rs754953589
- 0.0001 -
40_PHE TYR gnomAD
chr6:32489846 		rs150479833
- 0.00188581 -
40_PHE TYR 8.3kJPN
chr6:32489846 		rs150479833
- 0.0976 -
40_PHE TYR 8.3kJPN
chr6:32552050 		rs17882455
- 0.255 -
40_PHE VAL 8.3kJPN
chr6:32552051 		-
- 0.0001 -
41_ASP ASN gnomAD
chr6:32489844 		rs140580884
- 0.000470975 -
41_ASP ASN 8.3kJPN
chr6:32489844 		rs140580884
- 0.0939 -
41_ASP ASN 8.3kJPN
chr6:32552048 		rs56158521
- 0.3257 -
42_SER GLY 8.3kJPN
chr6:32489841 		-
- 0.0001 -
44_VAL LEU gnomAD
chr6:32489835 		rs118111025
- 0.0275528 -
44_VAL LEU gnomAD
chr6:32552039 		rs150747106
- 0.00175038 -
44_VAL MET gnomAD
chr6:32552039 		rs150747106
- 0.147503 -
44_VAL MET 8.3kJPN
chr6:32489835 		rs118111025
- - -
44_VAL MET 8.3kJPN
chr6:32552039 		rs150747106
- - -
45_GLY ARG 8.3kJPN
chr6:32552036 		rs17885437
- 0.0001 -
47_TYR PHE gnomAD
chr6:32489825 		rs148834340
- 0.0977658 -
47_PHE TYR gnomAD
chr6:32552029 		rs17884945
- 0.314464 -
47_TYR PHE 8.3kJPN
chr6:32489825 		rs148834340
- 0.0443 -
47_PHE TYR 8.3kJPN
chr6:32552029 		rs17884945
- 0.5244 -
48_ARG GLN gnomAD
chr6:32489822 		rs115417906
- 0.0289843 -
48_ARG GLN 8.3kJPN
chr6:32489822 		rs115417906
- 0.0773 -
48_ARG GLN 8.3kJPN
chr6:32552026 		rs17886436
- 0.2556 -
50_VAL ALA gnomAD
chr6:32552020 		rs17885908
- 0.00264425 -
51_THR ARG gnomAD
chr6:32489813 		rs79606458
- 0.0176113 -
51_THR ARG gnomAD
chr6:32552017 		rs1059582
- 0.000126062 -
51_THR ARG 8.3kJPN
chr6:32489813 		rs79606458
- 0.0196 -
51_THR ARG 8.3kJPN
chr6:32552017 		rs1059582
- 0.0609 -
52_GLU VAL ClinVar
chr6:32552014 		-
Pathogenic - Pulmonary artery atresia [Human Phenotype Ontology:HP:0004935,MedGen:C0265908]
57_ASP VAL gnomAD
chr6:32489795 		rs144532965
- 0.0113368 -
57_ASP GLY gnomAD
chr6:32489795 		rs144532965
- 0.0395773 -
57_ASP ALA gnomAD
chr6:32489795 		rs144532965
- 0.000118267 -
57_ASP ASN gnomAD
chr6:32489796 		rs145586726
- 0.0350737 -
57_ASP VAL gnomAD
chr6:32551999 		rs17885129
- 0.00835667 -
57_ASP GLY gnomAD
chr6:32551999 		rs17885129
- 0.00650247 -
57_ASP ALA gnomAD
chr6:32551999 		rs17885129
- 0.00835028 -
57_ASP ASN gnomAD
chr6:32552000 		rs17880292
- 0.00566168 -
57_ASP VAL 8.3kJPN
chr6:32489795 		rs144532965
- - -
57_ASP ASN 8.3kJPN
chr6:32489796 		rs145586726
- 0.1956 -
57_ASP VAL 8.3kJPN
chr6:32551999 		rs17885129
- - -
57_ASP ASN 8.3kJPN
chr6:32552000 		rs17880292
- 0.123 -
58_ALA ASP gnomAD
chr6:32489792 		rs41562816
- 0.113137 -
58_ALA ASP gnomAD
chr6:32551996 		rs1059584
- 0.0098369 -
58_ALA ASP 8.3kJPN
chr6:32489792 		rs41562816
- 0.0246 -
58_ALA ASP 8.3kJPN
chr6:32551996 		rs1059584
- 0.0026 -
60_TYR SER gnomAD
chr6:32489786 		rs41541218
- 0.012153 -
60_TYR SER gnomAD
chr6:32551990 		rs1059586
- 0.00564727 -
60_TYR HIS gnomAD
chr6:32551991 		rs17882583
- 0.007458 -
60_TYR SER 8.3kJPN
chr6:32489786 		rs41541218
- 0.1506 -
60_TYR HIS 8.3kJPN
chr6:32489787 		rs746070999
- - -
60_TYR SER 8.3kJPN
chr6:32551990 		rs1059586
- 0.1099 -
60_TYR HIS 8.3kJPN
chr6:32551991 		rs17882583
- 0.0417 -
61_TRP ARG 8.3kJPN
chr6:32551988 		-
- 0.0001 -
67_PHE LEU gnomAD
chr6:32489766 		rs696318
- 0.0565996 -
67_PHE ILE gnomAD
chr6:32489766 		rs696318
- 0.0461624 -
67_ILE PHE gnomAD
chr6:32551970 		rs17886918
- 0.00867543 -
67_ILE LEU gnomAD
chr6:32551970 		rs17886918
- 0.201872 -
67_PHE ILE 8.3kJPN
chr6:32489766 		rs696318
- - -
67_ILE PHE 8.3kJPN
chr6:32551970 		rs17886918
- - -
69_GLU ALA 8.3kJPN
chr6:32489759 		rs764618537
- 0.0004 -
69_GLU TER 8.3kJPN
chr6:32551964 		-
- 0.0001 -
70_ASP GLU gnomAD
chr6:32489755 		rs41559913
- 0.00041613 -
70_ASP GLU 8.3kJPN
chr6:32489755 		rs41559913
- 0.0013 -
71_ARG THR gnomAD
chr6:32489753 		rs41544215
- 0.00199454 -
71_ARG LYS gnomAD
chr6:32489753 		rs41544215
- 0.0548634 -
71_ARG GLY gnomAD
chr6:32489754 		rs41551116
- 0.0377136 -
71_ALA GLY gnomAD
chr6:32551957 		rs9269942
- 0.191881 -
71_ALA GLU gnomAD
chr6:32551957 		rs9269942
- 0.0233567 -
71_ALA THR gnomAD
chr6:32551958 		rs1064592
- 0.352483 -
71_ARG SER 8.3kJPN
chr6:32489752 		rs143737208
- 0.0003 -
71_ARG LYS 8.3kJPN
chr6:32489753 		rs41544215
- 0.0291 -
71_ARG GLY 8.3kJPN
chr6:32489754 		rs41551116
- 0.0588 -
71_ALA GLU 8.3kJPN
chr6:32551957 		rs9269942
- - -
71_ALA THR 8.3kJPN
chr6:32551958 		rs1064592
- 0.3453 -
72_ARG GLY 8.3kJPN
chr6:32489751 		rs149410716
- 0.0003 -
72_ARG TRP 8.3kJPN
chr6:32551955 		rs17885222
- 0.0016 -
74_ALA VAL gnomAD
chr6:32489744 		rs1059598
- 0.0855483 -
74_ALA GLU gnomAD
chr6:32489744 		rs1059598
- 0.00996973 -
74_ALA PRO gnomAD
chr6:32489745 		rs41548618
- 0.0829852 -
74_ALA VAL gnomAD
chr6:32551948 		rs17886882
- 0.000898266 -
74_ALA GLU gnomAD
chr6:32551948 		rs17886882
- 0.118064 -
74_ALA PRO gnomAD
chr6:32551949 		rs16822805
- 0.000608804 -
74_ALA THR gnomAD
chr6:32551949 		rs16822805
- 0.00761005 -
74_ALA VAL 8.3kJPN
chr6:32489744 		rs1059598
- - -
74_ALA THR 8.3kJPN
chr6:32489745 		rs41548618
- - -
74_ALA VAL 8.3kJPN
chr6:32551948 		rs17886882
- - -
74_ALA THR 8.3kJPN
chr6:32551949 		rs16822805
- - -
76_ASP GLY 8.3kJPN
chr6:32489738 		rs776845219
- 0.0005 -
76_ASP GLY 8.3kJPN
chr6:32551942 		rs767943289
- 0.0107 -
77_THR ASN gnomAD
chr6:32489735 		rs115817940
- 0.00716526 -
77_THR ASN gnomAD
chr6:32551939 		rs9269941
- 0.0159839 -
77_THR ASN 8.3kJPN
chr6:32489735 		rs115817940
- 0.1034 -
77_THR ASN 8.3kJPN
chr6:32551939 		rs9269941
- 0.1856 -
78_TYR PHE gnomAD
chr6:32489732 		rs1064677
- 0.00221315 -
78_TYR ASP gnomAD
chr6:32489733 		rs1064595
- 0.00223623 -
78_TYR PHE 8.3kJPN
chr6:32489732 		rs1064677
- 0.0872 -
78_TYR ASP 8.3kJPN
chr6:32489733 		rs1064595
- 0.0873 -
78_TYR PHE 8.3kJPN
chr6:32551936 		rs17879620
- - -
78_TYR ASP 8.3kJPN
chr6:32551937 		rs17884043
- 0.0002 -
80_ARG LYS 8.3kJPN
chr6:32489726 		-
- 0.0001 -
81_HIS TYR gnomAD
chr6:32489724 		rs142908883
- 0.00047137 -
81_HIS TYR gnomAD
chr6:32551928 		rs29029549
- 0.0450279 -
81_HIS TYR 8.3kJPN
chr6:32489724 		rs142908883
- 0.0154 -
81_HIS ARG 8.3kJPN
chr6:32551927 		-
- 0.0001 -
81_HIS TYR 8.3kJPN
chr6:32551928 		rs29029549
- - -
85_VAL ALA gnomAD
chr6:32551915 		rs17424145
- 0.0203139 -
85_VAL ALA 8.3kJPN
chr6:32489711 		rs1136778
- 0.0108 -
85_VAL ALA 8.3kJPN
chr6:32551915 		rs17424145
- 0.0444 -
86_VAL GLY gnomAD
chr6:32551912 		rs17885482
- 0.0854845 -
86_GLY VAL 8.3kJPN
chr6:32489708 		rs41556512
- 0.0228 -
86_VAL GLY 8.3kJPN
chr6:32551912 		rs17885482
- 0.2507 -
89_PHE LEU 8.3kJPN
chr6:32489700 		-
- 0.0001 -
96_GLU ASP gnomAD
chr6:32487424 		rs141474277
- 0.00907456 -
96_GLN HIS gnomAD
chr6:32549611 		rs1071752
- 0.501137 -
96_GLU ASP 8.3kJPN
chr6:32487424 		rs141474277
- - -
96_GLU TER 8.3kJPN
chr6:32487426 		rs1071751
- - -
96_GLN HIS 8.3kJPN
chr6:32549611 		rs1071752
- - -
96_GLN TER 8.3kJPN
chr6:32549613 		rs17882084
- - -
98_LYS GLU gnomAD
chr6:32487420 		rs138786370
- 0.0369287 -
98_LYS GLN gnomAD
chr6:32487420 		rs138786370
- 0.014728 -
98_LYS GLU gnomAD
chr6:32549607 		rs17405219
- 0.00318656 -
98_LYS GLN gnomAD
chr6:32549607 		rs17405219
- 0.0903753 -
98_LYS GLN 8.3kJPN
chr6:32487420 		rs138786370
- - -
98_LYS GLN 8.3kJPN
chr6:32549607 		rs17405219
- - -
102_TYR CYS 8.3kJPN
chr6:32549594 		rs1195941088
- 0.0001 -
104_ALA VAL gnomAD
chr6:32487401 		rs758743151
- 0.000169048 -
104_ALA SER gnomAD
chr6:32487402 		rs114131132
- 0.144843 -
104_ALA VAL 8.3kJPN
chr6:32487401 		rs758743151
- 0.014 -
104_ALA SER 8.3kJPN
chr6:32487402 		rs114131132
- 0.0271 -
104_SER LEU 8.3kJPN
chr6:32549588 		rs201929247
- 0.2775 -
104_SER ALA 8.3kJPN
chr6:32549589 		rs2308760
- 0.3891 -
105_ARG LYS gnomAD
chr6:32487398 		rs115198947
- 0.378218 -
105_ARG LYS 8.3kJPN
chr6:32487398 		rs115198947
- 0.5764 -
120_ASN SER gnomAD
chr6:32487353 		rs114293611
- 0.126415 -
120_ASN SER 8.3kJPN
chr6:32487353 		rs114293611
- 0.3118 -
120_SER ASN 8.3kJPN
chr6:32549540 		rs1059351
- 0.2977 -
123_TYR CYS 8.3kJPN
chr6:32487344 		rs201863832
- 0.1009 -
123_TYR CYS 8.3kJPN
chr6:32549531 		rs112796209
- 0.2949 -
125_GLY ALA gnomAD
chr6:32549525 		rs16822698
- 0.113657 -
125_GLY ALA 8.3kJPN
chr6:32487338 		rs113395425
- 0.1018 -
125_GLY ALA 8.3kJPN
chr6:32549525 		rs16822698
- 0.2962 -
127_ILE VAL gnomAD
chr6:32549520 		rs202047044
- 0.00606299 -
127_ILE VAL 8.3kJPN
chr6:32487333 		rs199986849
- 0.1025 -
127_ILE VAL 8.3kJPN
chr6:32549520 		rs202047044
- 0.2104 -
133_LEU ARG gnomAD
chr6:32549501 		rs707954
- 0.655748 -
133_LEU GLN gnomAD
chr6:32549501 		rs707954
- 0.198249 -
133_ARG GLN 8.3kJPN
chr6:32487314 		rs201882312
- 0.1743 -
133_LEU GLN 8.3kJPN
chr6:32549501 		rs707954
- - -
135_SER GLY gnomAD
chr6:32487309 		rs1059633
- 0.773043 -
135_GLY SER gnomAD
chr6:32549496 		rs757966595
- 0.00286634 -
135_SER GLY 8.3kJPN
chr6:32487309 		rs1059633
- 0.7151 -
138_GLU LYS gnomAD
chr6:32487300 		rs141514736
- 0.000149782 -
140_ALA THR gnomAD
chr6:32487294 		rs75709987
- 0.28998 -
140_ALA THR 8.3kJPN
chr6:32487294 		rs75709987
- 0.2776 -
140_ALA THR 8.3kJPN
chr6:32549481 		rs78916069
- 0.3391 -
141_GLY VAL 8.3kJPN
chr6:32549477 		-
- 0.0001 -
142_MET VAL gnomAD
chr6:32549475 		rs701829
- 0.863959 -
142_MET VAL 8.3kJPN
chr6:32549475 		rs701829
- 0.8131 -
149_GLN HIS gnomAD
chr6:32487265 		rs139485758
- 0.00403901 -
149_GLN HIS gnomAD
chr6:32487265 		rs139485758
- 0.0667887 -
149_GLN HIS 8.3kJPN
chr6:32487265 		rs139485758
- - -
149_GLN HIS 8.3kJPN
chr6:32549452 		rs77637983
- - -
153_TRP TER 8.3kJPN
chr6:32549441 		-
- 0.0001 -
157_THR ILE gnomAD
chr6:32487242 		rs41559420
- 0.0298228 -
157_THR ILE 8.3kJPN
chr6:32487242 		rs41559420
- 0.0111 -
159_VAL MET gnomAD
chr6:32549424 		rs112116022
- 0.0380135 -
159_VAL MET 8.3kJPN
chr6:32487237 		rs192264100
- 0.1504 -
159_VAL MET 8.3kJPN
chr6:32549424 		rs112116022
- 0.2358 -
166_ARG GLN gnomAD
chr6:32487215 		rs148933006
- 0.0158838 -
166_ARG GLN gnomAD
chr6:32549402 		rs3205588
- 0.0738165 -
166_ARG GLN 8.3kJPN
chr6:32487215 		rs148933006
- 0.0508 -
166_ARG GLN 8.3kJPN
chr6:32549402 		rs3205588
- 0.1624 -
168_GLY ALA 8.3kJPN
chr6:32487209 		rs189435670
- 0.2772 -
168_GLY ALA 8.3kJPN
chr6:32549396 		rs2308775
- 0.1814 -
172_THR SER 8.3kJPN
chr6:32549385 		-
- 0.0001 -
175_VAL LEU 8.3kJPN
chr6:32487189 		rs201575183
- 0.2812 -
175_VAL LEU 8.3kJPN
chr6:32549376 		rs36044702
- 0.1709 -
176_GLU LYS 8.3kJPN
chr6:32487186 		rs772100213
- 0.0002 -
180_VAL LEU gnomAD
chr6:32487174 		rs112872773
- 0.186502 -
180_VAL MET gnomAD
chr6:32487174 		rs112872773
- 0.0185597 -
180_VAL LEU gnomAD
chr6:32549361 		rs111739605
- 0.000737479 -
180_VAL MET gnomAD
chr6:32549361 		rs111739605
- 0.130972 -
180_VAL MET 8.3kJPN
chr6:32487174 		rs112872773
- - -
180_VAL MET 8.3kJPN
chr6:32549361 		rs111739605
- - -
181_THR MET gnomAD
chr6:32487170 		rs1136633
- 0.170325 -
181_THR ILE gnomAD
chr6:32549357 		rs200809587
- 0.147837 -
181_THR MET 8.3kJPN
chr6:32487170 		rs1136633
- 0.3647 -
181_THR ILE 8.3kJPN
chr6:32549357 		rs200809587
- 0.3785 -
182_SER ARG 8.3kJPN
chr6:32487166 		-
- 0.0002 -
182_SER ARG 8.3kJPN
chr6:32549353 		-
- 0.0002 -
183_PRO ALA gnomAD
chr6:32487165 		rs142204283
- 0.0631835 -
183_PRO ALA gnomAD
chr6:32549352 		rs1136846
- 0.00757603 -
183_PRO LEU 8.3kJPN
chr6:32487164 		rs111541713
- 0.2886 -
183_PRO ALA 8.3kJPN
chr6:32487165 		rs142204283
- 0.0255 -
183_PRO LEU 8.3kJPN
chr6:32549351 		rs17885501
- 0.1569 -
183_PRO ALA 8.3kJPN
chr6:32549352 		rs1136846
- 0.0469 -
185_THR ILE 8.3kJPN
chr6:32549345 		rs752658977
- 0.0002 -
187_GLU GLN gnomAD
chr6:32549340 		rs33936261
- 0.128889 -
187_GLU GLN 8.3kJPN
chr6:32487153 		rs112024745
- 0.0853 -
187_GLU GLN 8.3kJPN
chr6:32549340 		rs33936261
- 0.3103 -
189_ARG SER 8.3kJPN
chr6:32548632 		rs1136881
- 0.2322 -
189_ARG GLY 8.3kJPN
chr6:32549334 		-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.