PiSITE

PDB ID	1A0N	CHAIN	B
Protein name	FYN
Uniprot Accession	P06241
The number of similar proteins	46
The number of binding states	6
The number of binding partners	4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding state	Binding partners
	1A0N (CHAIN: B)
1	Monomeric state
2	P03407
3	O60880
4	P06241
5	5ZAU
6	P06241 P06241

Downdload

Molecule viewer

Only interaction residues

#binding
partners

	4
	3
	2
	1
	0

Sequence information

1

GSTGVTLFVA

LYDYEARTED

DLSFHKGEKF

QILNSSEGDW

WEARSLTTGE

50

51

TGYIPSNYVA

PVDSIQAEE

100

Variants

	Residue	AA	Source / dbSNP	Clinical Significance	Allele Frequency (> 0.0001)	AlphaMissense pathogenicity	Disease name
	86_ILE	VAL	8.3kJPN chr18:751793 rs111416313	-	0.0002	-	-
	114_LYS	GLN	gnomAD chr18:751739 rs117449313	-	0.00550436	-	-
	125_THR	ILE	8.3kJPN chr1:27949553 rs34597831	-	0.0034	-	-
	135_ILE	PHE	8.3kJPN chr18:747990 -	-	0.0001	-	-
	145_SER	ARG	gnomAD chr1:27948108 rs35334091	-	0.000962349	0.9841	-
	145_SER	ARG	8.3kJPN chr1:27948108 rs35334091	-	0.0001	0.9841	-
	149_ALA	VAL	8.3kJPN chr18:747947 rs766059693	-	0.0001	0.9829	-

(Powered by wupsivus)

Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364