PDB ID 6ZL1     CHAIN A
Protein name Albumin
Uniprot Accession P02768
The number of similar proteins 152
The number of binding states 9
The number of binding partners 8

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
6ZL1 (CHAIN: A)
1 6ZL1  
2 Monomeric state
3 P02768  
4 4HGK  
5 5VNW  
6 2VDB  
7 P61769   P55899  
8 5FUO   5FUO  
9 P02768   P02768  

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Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MKWVTFISLL   FLFSSAYSRG   VFRRDAHKSE   VAHRFKDLGE   ENFKALVLIA   50
51   FAQYLQQCPF   EDHVKLVNEV   TEFAKTCVAD   ESAENCDKSL   HTLFGDKLCT   100
101   VATLRETYGE   MADCCAKQEP   ERNECFLQHK   KDNPNLPRLV   RPEVDVMCTA   150
151   FHDNTETFLK   KYLYEIARRH   PYFYAPELLF   FAKRYKAAFT   ECCQAADKAA   200
201   CLLPKLDELR   DEGKASSAKQ   RLKCASLQKF   GERAFKAWAV   ARLSQRFPKA   250
251   EFAEVSKLVT   DLTKVHTECC   HGDLLECADD   RADLAKYICE   NQDSISSKLK   300
301   ECCEKPLLEK   SHCIAEVEND   EMPADLPSLA   ADFVESKDVC   KNYAEAKDVF   350
351   LGMFLYEYAR   RHPDYSVVLL   LRLAKTYETT   LEKCCAAADP   HECYAKVFDE   400
401   FKPLVEEPQN   LIKQNCELFE   QLGEYKFQNA   LLVRYTKKVP   QVSTPTLVEV   450
451   SRNLGKVGSK   CCKHPEAKRM   PCAEDYLSVV   LNQLCVLHEK   TPVSDRVTKC   500
501   CTESLVNRRP   CFSALEVDET   YVPKEFNAGT   FTFHADICTL   SEKERQIKKQ   550
551   TALVELVKHK   PKATKEQLKA   VMDDFAAFVE   KCCKADDKET   CFAEEGKKLV   600
601   AASQAALGL           650

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
73_PHE TYR VAR_010657 -
LB/B - -
83_ALA VAL gnomAD
chr4:74272456 		rs200736287
- 0.000378338 -
84_GLU LYS VAR_000507 rs77050410
LB/B - -
87_ASP ASN VAR_000508 rs78574148
LB/B - -
90_LEU PRO VAR_013011 rs77892378
LP/P - Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999]
106_GLU LYS VAR_000509 rs80296402
LB/B - -
108_TYR CYS gnomAD
chr4:74274363 		rs142714816
- 0.000517236 -
121_GLU GLY VAR_014290 -
LB/B - -
143_GLU LYS VAR_000511 rs75522063
LB/B - -
146_VAL GLU VAR_013012 rs77752336
LB/B - -
152_HIS ARG VAR_000512 rs80095457
LB/B - -
177_GLU ASP gnomAD
chr4:74275120 		rs149432908
- 0.000441805 -
201_CYS PHE VAR_000513 rs77656691
LB/B - -
215_ALA THR VAR_014291 rs3210154
LB/B - -
215_ALA VAL VAR_014292 rs3204504
LB/B - -
220_GLN LEU VAR_014293 rs3210163
LB/B - -
242_ARG HIS VAR_000514 rs75002628
LP/P - Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999]
242_ARG PRO VAR_013013 rs75002628
LP/P - Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999]
249_LYS GLN VAR_000515 rs79804069
LB/B - -
264_LYS GLU VAR_000516 rs79377490
LB/B - -
292_GLN ARG VAR_000517 rs80002911
LB/B - -
293_ASP GLY VAR_000518 rs79744198
LB/B - -
300_LYS ASN VAR_000519 rs74718349
LB/B - -
306_PRO LEU gnomAD
chr4:74279210 		rs755199533
- 0.000198885 -
337_LYS ASN VAR_000520 rs72552710
LB/B - -
338_ASP GLY VAR_013014 rs76242087
LB/B - -
338_ASP VAL VAR_013015 rs76242087
LB/B - -
342_ASN LYS VAR_000521 rs77544362
LB/B - -
344_ALA THR VAR_000522 rs78953271
LB/B - -
345_GLU LYS VAR_000523 rs72552711
LB/B - -
357_GLU LYS VAR_000524 rs77354753
LB/B - -
378_GLU LYS VAR_000525 rs76593094
LB/B - -
382_GLU LYS VAR_000526 rs75791663
LB/B - -
383_LYS ASN VAR_013016 rs75069738
LB/B - -
387_ALA SER gnomAD
chr4:74280852 		rs149483745
- 0.000123362 -
389_ASP HIS VAR_000527 rs77187142
LB/B - -
389_ASP VAL VAR_000528 rs78538497
LB/B - -
396_LYS GLU VAR_000529 rs78166690
LB/B - -
399_ASP ASN VAR_000530 rs77514449
LB/B - -
400_GLU LYS VAR_000531 rs79047363
LB/B - -
400_GLU GLN VAR_000532 rs79047363
LB/B - -
406_GLU LYS VAR_000533 rs76483862
LB/B - -
420_GLU LYS VAR_014294 -
LB/B - -
434_ARG CYS VAR_013017 rs78575701
LB/B - -
490_LYS GLU VAR_014295 rs1063469
LB/B - -
503_GLU LYS VAR_000534 rs80259813
LB/B - -
509_ARG GLN gnomAD
chr4:74283902 		rs200002649
- 0.0001313 -
518_ASP ASN VAR_000535 rs75920790
LB/B - -
525_GLU LYS VAR_000536 rs75523493
LB/B - -
525_GLU LYS gnomAD
chr4:74283949 		rs75523493
- 0.000135334 -
557_VAL MET VAR_013018 rs78284052
LB/B - -
557_VAL MET gnomAD
chr4:74285240 		rs78284052
- 0.000271236 -
560_LYS GLU VAR_000538 rs77645174
LB/B - -
565_LYS GLU VAR_000539 rs80345158
LB/B - -
574_ASP GLY VAR_000540 rs79738788
LB/B - -
574_ASP ALA VAR_000541 rs79738788
LB/B - -
574_ASP GLY gnomAD
chr4:74285292 		rs79738788
- 0.0011262 -
584_LYS GLU VAR_013019 rs76671808
LB/B - -
587_ASP ASN VAR_000542 rs76587671
LB/B - -
589_GLU LYS VAR_000543 rs75709682
LB/B - -
594_GLU LYS VAR_000544 rs79228041
LB/B - -
597_LYS GLU VAR_000545 rs80106970
LB/B - -
598_LYS ASN VAR_000546 rs75738598
LB/B - -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.