| PDB ID | 6ZL1
|
CHAIN | A |
|---|---|---|---|
| Protein name | Albumin | ||
| Uniprot Accession | P02768 | ||
| The number of similar proteins | 152 | ||
| The number of binding states | 9 | ||
| The number of binding partners | 8 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 6ZL1 (CHAIN: A) | |
| 1 |
6ZL1
|
| 2 | Monomeric state |
| 3 |
P02768
|
| 4 |
4HGK
|
| 5 |
5VNW
|
| 6 |
2VDB
|
| 7 |
P61769
P55899
|
| 8 |
5FUO
5FUO
|
| 9 |
P02768
P02768
|
Downdload
Molecule viewer
|
Only interaction residues |
|
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|
Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 73_PHE | TYR |
VAR_010657
- |
LB/B | - | 0.3031 | - | |
| 83_ALA | VAL |
gnomAD chr4:74272456 rs200736287 |
- | 0.000378338 | 0.2452 | - | |
| 84_GLU | LYS |
VAR_000507
rs77050410 |
LB/B | - | 0.1068 | - | |
| 87_ASP | ASN |
VAR_000508
rs78574148 |
LB/B | - | 0.1088 | - | |
| 90_LEU | PRO |
VAR_013011
rs77892378 |
LP/P | - | 0.692 | Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999] | |
| 106_GLU | LYS |
VAR_000509
rs80296402 |
LB/B | - | 0.202 | - | |
| 108_TYR | CYS |
gnomAD chr4:74274363 rs142714816 |
- | 0.000517236 | 0.7656 | - | |
| 121_GLU | GLY |
VAR_014290
- |
LB/B | - | 0.1606 | - | |
| 143_GLU | LYS |
VAR_000511
rs75522063 |
LB/B | - | 0.1999 | - | |
| 146_VAL | GLU |
VAR_013012
rs77752336 |
LB/B | - | 0.132 | - | |
| 152_HIS | ARG |
VAR_000512
rs80095457 |
LB/B | - | 0.0575 | - | |
| 177_GLU | ASP |
gnomAD chr4:74275120 rs149432908 |
- | 0.000441805 | 0.6967 | - | |
| 201_CYS | PHE |
VAR_000513
rs77656691 |
LB/B | - | 0.9228 | - | |
| 215_ALA | THR |
VAR_014291
rs3210154 |
LB/B | - | 0.082 | - | |
| 215_ALA | VAL |
VAR_014292
rs3204504 |
LB/B | - | 0.0931 | - | |
| 220_GLN | LEU |
VAR_014293
rs3210163 |
LB/B | - | 0.6372 | - | |
| 242_ARG | HIS |
VAR_000514
rs75002628 |
LP/P | - | 0.1194 | Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999] | |
| 242_ARG | PRO |
VAR_013013
rs75002628 |
LP/P | - | 0.9256 | Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999] | |
| 249_LYS | GLN |
VAR_000515
rs79804069 |
LB/B | - | 0.1445 | - | |
| 264_LYS | GLU |
VAR_000516
rs79377490 |
LB/B | - | 0.2466 | - | |
| 292_GLN | ARG |
VAR_000517
rs80002911 |
LB/B | - | 0.1286 | - | |
| 293_ASP | GLY |
VAR_000518
rs79744198 |
LB/B | - | 0.1121 | - | |
| 300_LYS | ASN |
VAR_000519
rs74718349 |
LB/B | - | 0.3778 | - | |
| 306_PRO | LEU |
gnomAD chr4:74279210 rs755199533 |
- | 0.000198885 | 0.346 | - | |
| 337_LYS | ASN |
VAR_000520
rs72552710 |
LB/B | - | 0.3203 | - | |
| 338_ASP | GLY |
VAR_013014
rs76242087 |
LB/B | - | 0.215 | - | |
| 338_ASP | VAL |
VAR_013015
rs76242087 |
LB/B | - | 0.324 | - | |
| 342_ASN | LYS |
VAR_000521
rs77544362 |
LB/B | - | 0.4231 | - | |
| 344_ALA | THR |
VAR_000522
rs78953271 |
LB/B | - | 0.069 | - | |
| 345_GLU | LYS |
VAR_000523
rs72552711 |
LB/B | - | 0.2073 | - | |
| 357_GLU | LYS |
VAR_000524
rs77354753 |
LB/B | - | 0.8085 | - | |
| 378_GLU | LYS |
VAR_000525
rs76593094 |
LB/B | - | 0.7051 | - | |
| 382_GLU | LYS |
VAR_000526
rs75791663 |
LB/B | - | 0.2462 | - | |
| 383_LYS | ASN |
VAR_013016
rs75069738 |
LB/B | - | 0.1979 | - | |
| 387_ALA | SER |
gnomAD chr4:74280852 rs149483745 |
- | 0.000123362 | 0.0739 | - | |
| 389_ASP | HIS |
VAR_000527
rs77187142 |
LB/B | - | 0.2836 | - | |
| 389_ASP | VAL |
VAR_000528
rs78538497 |
LB/B | - | 0.2332 | - | |
| 396_LYS | GLU |
VAR_000529
rs78166690 |
LB/B | - | 0.1555 | - | |
| 399_ASP | ASN |
VAR_000530
rs77514449 |
LB/B | - | 0.1121 | - | |
| 400_GLU | LYS |
VAR_000531
rs79047363 |
LB/B | - | 0.1505 | - | |
| 400_GLU | GLN |
VAR_000532
rs79047363 |
LB/B | - | 0.1213 | - | |
| 406_GLU | LYS |
VAR_000533
rs76483862 |
LB/B | - | 0.1407 | - | |
| 420_GLU | LYS |
VAR_014294
- |
LB/B | - | 0.1538 | - | |
| 434_ARG | CYS |
VAR_013017
rs78575701 |
LB/B | - | 0.5955 | - | |
| 490_LYS | GLU |
VAR_014295
rs1063469 |
LB/B | - | 0.3701 | - | |
| 503_GLU | LYS |
VAR_000534
rs80259813 |
LB/B | - | 0.1933 | - | |
| 509_ARG | GLN |
gnomAD chr4:74283902 rs200002649 |
- | 0.0001313 | 0.4197 | - | |
| 518_ASP | ASN |
VAR_000535
rs75920790 |
LB/B | - | 0.4854 | - | |
| 525_GLU | LYS |
VAR_000536
rs75523493 |
LB/B | - | 0.1237 | - | |
| 525_GLU | LYS |
gnomAD chr4:74283949 rs75523493 |
- | 0.000135334 | 0.1237 | - | |
| 557_VAL | MET |
VAR_013018
rs78284052 |
LB/B | - | 0.3933 | - | |
| 557_VAL | MET |
gnomAD chr4:74285240 rs78284052 |
- | 0.000271236 | 0.3933 | - | |
| 560_LYS | GLU |
VAR_000538
rs77645174 |
LB/B | - | 0.6077 | - | |
| 565_LYS | GLU |
VAR_000539
rs80345158 |
LB/B | - | 0.0572 | - | |
| 574_ASP | GLY |
VAR_000540
rs79738788 |
LB/B | - | 0.1348 | - | |
| 574_ASP | ALA |
VAR_000541
rs79738788 |
LB/B | - | 0.1925 | - | |
| 574_ASP | GLY |
gnomAD chr4:74285292 rs79738788 |
- | 0.0011262 | 0.1348 | - | |
| 584_LYS | GLU |
VAR_013019
rs76671808 |
LB/B | - | 0.105 | - | |
| 587_ASP | ASN |
VAR_000542
rs76587671 |
LB/B | - | 0.0906 | - | |
| 589_GLU | LYS |
VAR_000543
rs75709682 |
LB/B | - | 0.3444 | - | |
| 594_GLU | LYS |
VAR_000544
rs79228041 |
LB/B | - | 0.1085 | - | |
| 597_LYS | GLU |
VAR_000545
rs80106970 |
LB/B | - | 0.0839 | - | |
| 598_LYS | ASN |
VAR_000546
rs75738598 |
LB/B | - | 0.1944 | - |