PDB ID 6R15     CHAIN A
Protein name SUN domain-containing protein 1
Uniprot Accession O94901
The number of similar proteins 17
The number of binding states 9
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
6R15 (CHAIN: A)
1 Q8NF91  
2 6R2I  
3 O94901   O94901  
4 O94901   O94901   Q12912  
5 O94901   O94901   Q8N205   Q8N205  
6 O94901   O94901   Q12912   Q12912  
7 O94901   O94901   Q8N205   Q8N205   Q8N205  
8 O94901   O94901   Q12912   Q12912   Q12912  
9 O94901   O94901   Q8N205   Q8N205   Q8N205   Q8N205  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  5
  4
  3
  2
  1
  0

Sequence information

1   GSGGSGGITE   AQARAIVNSA   LKLYSQDKTG   MVDFALESGG   GSILSTRCSE   50
51   TYETKTALMS   LFGIPLWYFS   QSPRVVIQPD   IYPGNCWAFK   GSQGYLVVRL   100
101   SMMIHPAAFT   LEHIPKTLSP   TGNISSAPKD   FAVYGLENEY   QEEGQLLGQF   150
151   TYDQDGESLQ   MFQALKRPDD   TAFQIVELRI   FSNWGHPEYT   CLYRFRVHGE   200
201   PVK           250

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
621_GLN HIS 8.3kJPN
chr7:901019
-
- 0.0001 - -
679_SER LEU 8.3kJPN
chr7:905679
rs747017149
- 0.0001 - -
712_MET THR 8.3kJPN
chr7:909059
-
- 0.0001 - -
732_ASN SER gnomAD
chr7:909119
rs138051124
- 0.00108344 - -
739_ASP GLU 8.3kJPN
chr7:909141
rs1467957722
- 0.0001 - -
742_VAL ILE gnomAD
chr7:909148
rs200907784
- 0.000837184 - -
750_GLN GLU 8.3kJPN
chr7:912125
-
- 0.0001 - -
760_THR MET gnomAD
chr7:912156
rs201199820
- 0.000235288 - -
760_THR MET 8.3kJPN
chr7:912156
rs201199820
- 0.0017 - -
773_ALA VAL gnomAD
chr7:912195
rs189728809
- 0.000312644 - -
778_ASP ASN gnomAD
chr7:912861
rs200503893
- 0.000220421 - -
779_ASP ASN 8.3kJPN
chr7:912864
rs768700424
- 0.0003 - -
788_ARG GLN gnomAD
chr7:912892
rs199515429
- 0.000508879 - -
789_ILE VAL 8.3kJPN
chr7:912894
-
- 0.0001 - -
801_LEU PRO 8.3kJPN
chr7:912931
-
- 0.0001 0.0666 -
809_GLU LYS 8.3kJPN
chr7:912954
rs373928196
- 0.0008 - -
812_LYS ARG 8.3kJPN
chr7:912964
-
- 0.0001 - -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.