| PDB ID | 6NJZ
|
CHAIN | A |
|---|---|---|---|
| Protein name | Ephrin type-A receptor 2 | ||
| Uniprot Accession | P29317 | ||
| The number of similar proteins | 18 | ||
| The number of binding states | 7 | ||
| The number of binding partners | 8 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 6NJZ (CHAIN: A) | |
| 1 | Monomeric state |
| 2 |
P20827
|
| 3 |
P03212
P03231
|
| 4 |
Q98142
Q76RG7
|
| 5 |
P29317
P29317
|
| 6 |
3SKJ
3SKJ
|
| 7 |
Q76RG7
Q98142
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 40_GLU | VAL |
8.3kJPN chr1:16477425 rs1557516913 |
- | 0.0003 | 0.7199 | - | |
| 41_LEU | VAL |
gnomAD chr1:16477423 rs147977279 |
- | 0.00201257 | 0.4159 | - | |
| 93_ARG | CYS |
gnomAD chr1:16475419 rs200152244 |
- | 0.000350026 | 0.6643 | - | |
| 99_LYS | ASN |
VAR_055989
rs1058372 |
LB/B | - | 0.5916 | - | |
| 104_ASP | GLY |
8.3kJPN chr1:16475385 - |
- | 0.0001 | 0.919 | - | |
| 104_ASP | TYR |
8.3kJPN chr1:16475386 - |
- | 0.0001 | 0.9347 | - | |
| 150_ILE | LEU |
8.3kJPN chr1:16475248 - |
- | - | 0.5185 | - | |
| 156_PHE | LEU |
8.3kJPN chr1:16475228 - |
- | 0.0001 | 0.7715 | - | |
| 157_GLU | LYS |
8.3kJPN chr1:16475227 rs764156192 |
- | 0.0001 | 0.0938 | - | |
| 165_VAL | MET |
gnomAD chr1:16475203 rs150790360 |
- | 0.00137229 | 0.1204 | - | |
| 165_VAL | MET |
8.3kJPN chr1:16475203 rs150790360 |
- | 0.0001 | 0.1204 | - | |
| 172_PRO | LEU |
gnomAD chr1:16475181 rs751025996 |
- | 0.000156264 | 0.1326 | - | |
| 175_ARG | CYS |
gnomAD chr1:16475173 rs147352564 |
- | 0.000385415 | 0.1922 | - |