PDB ID 5VIX     CHAIN A
Protein name Polyubiquitin
Uniprot Accession D2V6G7
The number of similar proteins 28
The number of binding states 11
The number of binding partners 10

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
5VIX (CHAIN: A)
1 Monomeric state
2 P0CG48  
3 Q9WUB0  
4 Q96BN8  
5 B9G207  
6 6NJD  
7 Q9UK80  
8 E7FEV5  
9 Q8K3K8   Q8K3K8  
10 Q15025   Q15025  
11 B4DV12   F8L9T9   F8L9T9  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   MAHHHHHHMQ   IFVKTLTGKT   ITLEVESNDT   IENVKSKIQD   KEGIPPDQQR   50
51   LIFAGKQLED   GRTLSDYNIQ   KESTLHLVLR   LRGGMQIFVK   TLTGKTITLE   100
101   VESNDTIENV   KSKIQDKEGI   PPDQQRLIFA   GKQLEDGRTL   SDYNIQKEST   150
151   LHLVLRLRGG           200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
1_MET VAL 8.3kJPN
chr12:125398317 		rs1269760522
- 0.0001 -
2_GLN HIS 8.3kJPN
chr2:55459966 		rs370364740
- 0.0001 -
7_THR ILE 8.3kJPN
chr12:125398298 		-
- 0.0001 -
15_LEU PHE 8.3kJPN
chr12:125397591 		-
- 0.0001 -
19_PRO LEU 8.3kJPN
chr12:125397350 		rs762204446
- 0.0002 -
20_SER ASN 8.3kJPN
chr12:125396435 		-
- 0.0001 -
20_SER GLY 8.3kJPN
chr19:18684168 		-
- 0.0003 -
26_VAL ILE 8.3kJPN
chr12:125397558 		rs150983258
- 0.0012 -
37_PRO LEU 8.3kJPN
chr12:125397524 		-
- 0.0001 -
37_PRO SER 8.3kJPN
chr12:125397753 		rs1566302337
- 0.0001 -
38_SER PRO gnomAD
chr12:125397750 		rs7137123
- 0.999936 -
55_THR ILE 8.3kJPN
chr2:55461315 		-
- 0.0001 -
57_SER PRO gnomAD
chr2:55461320 		rs11557872
- 0.000975396 -
61_ILE THR 8.3kJPN
chr12:125396312 		-
- 0.0001 -
67_LEU MET 8.3kJPN
chr12:125397207 		rs201589267
- - -
73_LEU PHE 8.3kJPN
chr12:125397189 		rs986458417
- 0.0001 -
76_GLY ASP 8.3kJPN
chr12:125396267 		-
- 0.0001 -
78_GLN HIS 8.3kJPN
chr2:55459966 		rs370364740
- 0.0001 -
91_LEU PHE 8.3kJPN
chr12:125397591 		-
- 0.0001 -
95_PRO LEU 8.3kJPN
chr12:125397350 		rs762204446
- 0.0002 -
96_SER ASN 8.3kJPN
chr12:125396435 		-
- 0.0001 -
96_SER GLY 8.3kJPN
chr19:18684168 		-
- 0.0003 -
102_VAL ILE 8.3kJPN
chr12:125397558 		rs150983258
- 0.0012 -
113_PRO LEU 8.3kJPN
chr12:125397524 		-
- 0.0001 -
113_PRO SER 8.3kJPN
chr12:125397753 		rs1566302337
- 0.0001 -
114_SER PRO gnomAD
chr12:125397750 		rs7137123
- 0.999936 -
115_ASP ASN 8.3kJPN
chr17:16285792 		rs1466274713
- 0.0003 -
131_THR ILE 8.3kJPN
chr2:55461315 		-
- 0.0001 -
133_SER PRO gnomAD
chr2:55461320 		rs11557872
- 0.000975396 -
137_ILE THR 8.3kJPN
chr12:125396312 		-
- 0.0001 -
143_LEU MET 8.3kJPN
chr12:125397207 		rs201589267
- - -
149_LEU PHE 8.3kJPN
chr12:125397189 		rs986458417
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.