| PDB ID | 5O8K
|
CHAIN | A |
|---|---|---|---|
| Protein name | Mitotic spindle assembly checkpoint protein MAD2B | ||
| Uniprot Accession | Q9D752 | ||
| The number of similar proteins | 30 | ||
| The number of binding states | 9 | ||
| The number of binding partners | 6 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 5O8K (CHAIN: A) | |
| 1 | Monomeric state |
| 2 |
O60673
|
| 3 |
Q6ZNX1
|
| 4 |
Q9UBZ9
|
| 5 |
Q9UI95
Q6ZNX1
|
| 6 |
Q9UBZ9
O60673
|
| 7 |
Q9UI95
Q86V20
Q6ZNX1
|
| 8 |
Q9UI95
Q6ZNX1
Q6ZNX1
|
| 9 |
Q9UI95
Q6ZNX1
Q6ZNX1
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 8_ASP | ASN |
8.3kJPN chr1:11740637 - |
- | 0.0001 | - | - | |
| 49_ASN | SER |
8.3kJPN chr1:11740423 - |
- | 0.0001 | - | - | |
| 51_PRO | GLN |
8.3kJPN chr1:11740417 - |
- | 0.0001 | - | - | |
| 85_VAL | GLU |
ClinVar chr1:11736983 rs1057517674 |
Pathogenic | - | - | Fanconi anemia complementation group V|not provided [MONDO:MONDO:0014985,MedGen:C4310652,OMIM:617243|MedGen:CN517202] | |
| 93_ARG | HIS |
gnomAD chr1:11736959 rs151024263 |
- | 0.000338225 | - | - | |
| 124_ARG | GLN |
8.3kJPN chr1:11736159 rs757723800 |
- | 0.0001 | - | - | |
| 182_HIS | ARG |
8.3kJPN chr1:11735188 - |
- | 0.0001 | - | - | |
| 206_ARG | CYS |
8.3kJPN chr1:11734852 rs142776270 |
- | 0.0001 | - | - |