PDB ID 5JLZ     CHAIN A
Protein name HLA class II histocompatibility antigen, DR alpha chain
Uniprot Accession P01903
The number of similar proteins 133
The number of binding states 16
The number of binding partners 9

Coloring

Unicolor (beige)

The number of binding partners

Group

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   IKEEHVIIQA   EFYLNPDQSG   EFMFDFDGDE   IFHVDMAKKE   TVWRLEEFGR   50
51   FASFEAQGAL   ANIAVDKANL   EIMTKRSNYT   PITNVPPEVT   VLTNSPVELR   100
101   EPNVLICFID   KFTPPVVNVT   WLRNGKPVTT   GVSETVFLPR   EDHLFRKFHY   150
151   LPFLPSTEDV   YDCRVEHWGL   DEPLLKHWEF   DSSADLVPR     200

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
5_HIS ARG 8.3kJPN
chr6:32410231
-
- 0.0001 -
76_ARG SER gnomAD
chr6:32410443
rs201781094
- 0.000287349 -
81_PRO LEU 8.3kJPN
chr6:32410459
rs754838655
- 0.0001 -
93_THR ILE 8.3kJPN
chr6:32410986
rs1407197550
- 0.0001 -
123_ARG GLN gnomAD
chr6:32411076
rs138462914
- 0.000576168 -
160_VAL ILE 8.3kJPN
chr6:32411186
rs200798853
- 0.0001 -
168_TRP ARG gnomAD
chr6:32411210
rs199723815
- 0.000150153 -
168_TRP ARG 8.3kJPN
chr6:32411210
rs199723815
- 0.0215 -
169_GLY SER 8.3kJPN
chr6:32411213
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.