| PDB ID | 5HI3
|
CHAIN | A |
|---|---|---|---|
| Protein name | Interleukin-17A | ||
| Uniprot Accession | Q16552 | ||
| The number of similar proteins | 46 | ||
| The number of binding states | 10 | ||
| The number of binding partners | 4 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 5HI3 (CHAIN: A) | |
| 1 |
2VXS
2VXS
2VXS
2VXS
|
| 2 | Monomeric state |
| 3 |
Q16552
|
| 4 |
8B7W
|
| 5 |
8DY1
|
| 6 |
6WIR
6WIR
|
| 7 |
Q96PD4
Q96F46
|
| 8 |
Q16552
5HHX
5HHX
|
| 9 |
Q16552
4QHU
4QHU
4QHU
|
| 10 |
Q16552
5N7W
5N7W
5N7W
5N7W
|
Downdload
Molecule viewer
|
Only interaction residues |
|
||||||||||||
|
Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 36_ASN | SER |
8.3kJPN chr6:52052549 rs746361396 |
- | 0.0001 | 0.0724 | - | |
| 37_PRO | LEU |
8.3kJPN chr6:52052552 - |
- | 0.0001 | 0.0912 | - | |
| 55_ARG | CYS |
8.3kJPN chr6:52053854 rs777451627 |
- | 0.0001 | 0.3884 | - | |
| 55_ARG | HIS |
8.3kJPN chr6:52053855 rs760902102 |
- | 0.0001 | 0.1533 | - | |
| 58_ASP | GLY |
8.3kJPN chr6:52053864 - |
- | 0.0001 | 0.9103 | - | |
| 68_GLU | LYS |
gnomAD chr6:52053893 rs151317528 |
- | 0.000131537 | 0.7943 | - | |
| 69_ALA | SER |
gnomAD chr6:52053896 rs763243057 |
- | 0.000139504 | 0.5105 | - | |
| 69_ALA | SER |
8.3kJPN chr6:52053896 rs763243057 |
- | 0.0012 | 0.5105 | - | |
| 72_ARG | CYS |
gnomAD chr6:52053905 rs199987410 |
- | 0.00108791 | 0.4972 | - | |
| 72_ARG | HIS |
gnomAD chr6:52053906 rs755641354 |
- | 0.000151464 | 0.172 | - | |
| 79_ALA | PRO |
8.3kJPN chr6:52053926 rs756965539 |
- | 0.0002 | 0.1912 | - | |
| 83_VAL | MET |
8.3kJPN chr6:52053938 rs745674559 |
- | 0.0001 | 0.1223 | - | |
| 111_ARG | GLN |
gnomAD chr6:52054023 rs147810050 |
- | 0.000518036 | 0.0878 | - |