PDB ID 4NFU     CHAIN A
Protein name EDS1
Uniprot Accession Q9XF23
The number of similar proteins 6
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
4NFU (CHAIN: A)
1 Q4F883  
2 6I8H  
3 Q9S745  
4 Q4F883   Q9FKZ2  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   MGSSHHHHHH   SQDPAFEALT   GINGDLITRS   WSASKQAYLT   ERYHKEEAGA   50
51   VVIFAFQPSF   SEKDFFDPDN   KSSFGEIKLN   RVQFPCMRKI   GKGDVATVNE   100
101   AFLKNLEAVI   DPRTSFQASV   EMAVRSRKQI   VFTGHSSGGA   TAILATVWYL   150
151   EKYFIRNPNV   YLEPRCVTFG   APLVGDSIFS   HALGREKWSR   FFVNFVTRFD   200
201   IVPRITLARK   ASVEETLPHV   LAQLDPRNSS   VQESEQRITE   FYTSVMRDTS   250
251   TVANQAVCEL   TGSAEAILET   LSSFLELSPY   RPAGTFVFST   EKRLVAVNNS   300
301   DAILQMLFYT   CQASDEQEWS   LIPFRSIRDH   HSYEELVQSM   GMKLFNHLDG   350
351   ENSIESSLND   LGVSTRGRQY   VQAALEEEKK   RVENQKKIIQ   VIQQERFLKK   400
401   LAWIEDEYKP   KCQAHKNGYY   DSFKVSNEEN   DFKANVKRAE   LAGVFDEVLG   450
451   LLKKCQLPDE   FEGDIDWIKL   ATRYRRLVEP   LDIANYHRHL   KNEDTGPYMK   500
501   RGRPTRYIYA   QRGYEHHILK   PNGMIAEDVF   WNKVNGLNLG   LQLEEIQETL   550
551   KNSGSECGSC   FWAEVEELKG   KPYEEVEVRV   KTLEGMLREW   ITAGEVDEKE   600
601   IFLEGSTFRK   WWITLPKNHK   SHSPLRDYMM   DEITDT     650

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.