PDB ID 3W3T     CHAIN A
Protein name Importin subunit beta-3
Uniprot Accession P32337
The number of similar proteins 9
The number of binding states 6
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3W3T (CHAIN: A)
1 Monomeric state
2 P13574  
3 Q03790  
4 Q00684  
5 Q02724  
6 P62825  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MSALPEEVNR   TLLQIVQAFA   SPDNQIRSVA   EKALSEEWIT   ENNIEYLLTF   50
51   LAEQAAFSQD   TTVAALSAVL   FRKLALKAPI   THIRKEVLAQ   IRSSLLKGFL   100
101   SERADSIRHK   LSDAIAECVQ   DDLPAWPELL   QALIESLKSG   NPNFRESSFR   150
151   ILTTVPYLIT   AVDINSILPI   FQSGFTDASD   NVKIAAVTAF   VGYFKQLPKS   200
201   EWSKLGILLP   SLLNSLPRFL   DDGKDDALAS   VFESLIELVE   LAPKLFKDMF   250
251   DQIIQFTDMV   IKNKDLEPPA   RTTALELLTV   FSENAPQMCK   SNQNYGQTLV   300
301   MVTLIMMTEV   SIDDDDAAEW   IESDDTDDEE   EVTYDHARQA   LDRVALKLGG   350
351   EYLAAPLFQY   LQQMITSTEW   RERFAAMMAL   SSAAEGCADV   LIGEIPKILD   400
401   MVIPLINDPH   PRVQYGCCNV   LGQISTDFSP   FIQRTAHDRI   LPALISKLTS   450
451   ECTSRVQTHA   AAALVNFSEF   ASKDILEPYL   DSLLTNLLVL   LQSNKLYVQE   500
501   QALTTIAFIA   EAAKNKFIKY   YDTLMPLLLN   VLKVNNKDNS   VLKGKCMECA   550
551   TLIGFAVGKE   KFHEHSQELI   SILVALQNSD   IDEDDALRSY   LEQSWSRICR   600
601   ILGDDFVPLL   PIVIPPLLIT   AKATQDVGLI   EEEEAANFQQ   YPDWDVVQVQ   650
651   GKHIAIHTSV   LDDKVSAMEL   LQSYATLLRG   QFAVYVKEVM   EEIALPSLDF   700
701   YLHDGVRAAG   ATLIPILLSC   LLAATGTQNE   ELVLLWHKAS   SKLIGGLMSE   750
751   PMPEITQVYH   NSLVNGIKVM   GDNCLSEDQL   AAFTKGVSAN   LTDTYERMQD   800
801   RHGDGDEYNE   NIDEEEDFTD   EDLLDEINKS   IAAVLKTTNG   HYLKNLENIW   850
851   PMINTFLLDN   EPILVIFALV   VIGDLIQYGG   EQTASMKNAF   IPKVTECLIS   900
901   PDARIRQAAS   YIIGVCAQYA   PSTYADVCIP   TLDTLVQIVD   FPGSKLEENR   950
951   SSTENASAAI   AKILYAYNSN   IPNVDTYTAN   WFKTLPTITD   KEAASFNYQF   1000
1001   LSQLIENNSP   IVCAQSNISA   VVDSVIQALN   ERSLTEREGQ   TVISSVKKLL   1050
1051   GFLPSSDAMA   IFNRYPADIM   EKVHKWFA       1100

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.