PDB ID 3TU1     CHAIN A
Protein name E3 ubiquitin-protein ligase Mdm2
Uniprot Accession Q00987
The number of similar proteins 108
The number of binding states 7
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3TU1 (CHAIN: A)
1 Monomeric state
2 Q00987  
3 Q328D2  
4 2M86  
5 P36649  
6 5WTS  
7 P35222  

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Only interaction residues
#binding
partners
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   QIPASEQETL   VRPKPLLLKL   LKSVGAQKDT   YTMKEVLFYL   GQYIMTKRLY   50
51   DEKQQHIVYC   SNDLLGDLFG   VPSFSVKEHR   KIYTMIYRNL   VVVNQQESSD   100
101   SGTSVSEN           150

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
38_LEU VAL 8.3kJPN
chr12:69207364
-
- 0.0001 0.8523 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.