PDB ID 3RK2     CHAIN A
Protein name Vesicle-associated membrane protein 2
Uniprot Accession P63027
The number of similar proteins 7
The number of binding states 3
The number of binding partners 5

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3RK2 (CHAIN: A)
1 P60880   P60880   P32851  
2 Q57236  
3 O14810   P60880   P60880   P32851  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   GPLGSNRRLQ   QTQAQVDEVV   DIMRVNVDKV   LERDQKL     50

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
32_LEU ARG 8.3kJPN
chr1:7833543
-
- 0.0001 0.9709 -
50_VAL MET 8.3kJPN
chr1:7837244
rs763888128
- 0.0001 0.9346 -
52_LYS GLU 8.3kJPN
chr1:7837250
-
- 0.0001 0.9786 -
56_ARG TER ClinVar
chr17:8065042
rs1289411487
Pathogenic - - not provided [MedGen:CN517202]
56_ARG LEU ClinVar
chr17:8065041
rs1983318892
Likely pathogenic - 0.9949 not provided [MedGen:CN517202]
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.