PDB ID 3Q0H     CHAIN A
Protein name T cell immunoreceptor with Ig and ITIM domains
Uniprot Accession Q495A1
The number of similar proteins 15
The number of binding states 7
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
3Q0H (CHAIN: A)
1 Monomeric state
2 Q495A1  
3 Q92692  
4 8VTE   8VTE  
5 8VTD   8VTD  
6 Q495A1   P15151  
7 8SZY   8SZY   8SZY   8SZY  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MMMTGTIETT   GNISAEKGGS   IILQCHLSST   TAQVTQVNWE   QQDQLLAICN   50
51   ADLGWHISPS   FKDRVAPGPG   LGLTLQSLTV   NDTGEYFCIY   HTYPDGTYTG   100
101   RIFLEVLESS   VAEHGAR         150

Variants

Residue AA Source /
dbSNP
Clinical
Significance
Allele
Frequency
(> 0.0001)
AlphaMissense
pathogenicity
Disease name
23_MET THR 8.3kJPN
chr3:114014398
-
- 0.0009 0.1496 -
33_ILE VAL VAR_056079
rs13098836
LB/B - 0.1025 -
33_ILE VAL gnomAD
chr3:114014427
rs13098836
- 0.00242388 0.1025 -
36_GLU LYS 8.3kJPN
chr3:114014436
rs142063959
- 0.0001 0.068 -
51_THR MET 8.3kJPN
chr3:114014482
rs200389176
- 0.0001 0.0706 -
75_TRP CYS gnomAD
chr3:114014555
rs202226565
- 0.000186929 0.7807 -
95_LEU PHE 8.3kJPN
chr3:114014613
rs539986801
- 0.0004 0.0896 -
100_VAL MET 8.3kJPN
chr3:114014628
rs207463547
- 0.0001 0.0623 -
102_ASP ASN 8.3kJPN
chr3:114014634
rs146935299
- 0.0028 0.7001 -
122_ILE THR 8.3kJPN
chr3:114014695
-
- 0.0006 0.6859 -
125_GLU LYS 8.3kJPN
chr3:114014703
-
- 0.0001 0.1085 -
126_VAL ILE 8.3kJPN
chr3:114014706
-
- 0.0001 0.1225 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.