PDB ID 3BIK     CHAIN A
Protein name Programmed cell death 1 ligand 1
Uniprot Accession Q9NZQ7
The number of similar proteins 18
The number of binding states 9
The number of binding partners 8

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3BIK (CHAIN: A)
1 Q02242  
2 Monomeric state
3 Q9NZQ7  
4 8AOM  
5 7XAE  
6 7XAD  
7 P33681  
8 7XYQ  
9 5GRJ   5GRJ  

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Only interaction residues
#binding
partners
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   AFTVTVPKDL   YVVEYGSNMT   IECKFPVEKQ   LDLAALIVYW   EMEDKNIIQF   50
51   VHGEEDLKVQ   HSSYRQRARL   LKDQLSLGNA   ALQITDVKLQ   DAGVYRCMIS   100
101   YGGADYKRIT   VKVNAPYNKI   NQRILVVDPV   TSEHELTCQA   EGYPKAEVIW   150
151   TSSDHQVLSG   KTTTTNSKRE   EKLFNVTSTL   RINTTTNEIF   YCTFRRLDPE   200
201   ENHTAELVIP   ELPLAHPPNE   RT       250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
22_THR MET gnomAD
chr9:5457091 		rs143235887
- 0.000100493 -
31_GLU GLN 8.3kJPN
chr9:5457117 		rs373692552
- 0.0001 -
113_ARG HIS 8.3kJPN
chr9:5457364 		rs1272843564
- 0.0001 -
136_LYS ASN 8.3kJPN
chr9:5462847 		-
- 0.0001 -
142_LEU SER 8.3kJPN
chr9:5462864 		rs1369526855
- 0.0004 -
146_PRO ARG gnomAD
chr9:5462876 		rs17718883
- 0.00393462 -
164_GLU LYS gnomAD
chr9:5462929 		rs146495642
- 0.000358306 -
224_LEU TRP 8.3kJPN
chr9:5463110 		-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.