PDB ID 2XU7     CHAIN A
Protein name HISTONE-BINDING PROTEIN RBBP4
Uniprot Accession Q09028
The number of similar proteins 33
The number of binding states 11
The number of binding partners 11

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2XU7 (CHAIN: A)
1 Monomeric state
2 Q13330  
3 Q13330  
4 Q13330  
5 Q13111  
6 Q15022  
7 Q09028  
8 Q96GY3   Q5TKA1  
9 Q13112   Q13111  
10 Q5T6S3   Q15022  
11 Q15022   Q6ZN18  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   MADKEAAFDD   AVEERVINEE   YKIWKKNTPF   LYDLVMTHAL   EWPSLTAQWL   50
51   PDVTRPEGKD   FSIHRLVLGT   HTSDEQNHLV   IASVQLPNDD   AQFDASHYDS   100
101   EKGEFGGFGS   VSGKIEIEIK   INHEGEVNRA   RYMPQNPCII   ATKTPSSDVL   150
151   VFDYTKHPSK   PDPSGECNPD   LRLRGHQKEG   YGLSWNPNLS   GHLLSASDDH   200
201   TICLWDISAV   PKEGKVVDAK   TIFTGHTAVV   EDVSWHLLHE   SLFGSVADDQ   250
251   KLMIWDTRSN   NTSKPSHSVD   AHTAEVNCLS   FNPYSEFILA   TGSADKTVAL   300
301   WDLRNLKLKL   HSFESHKDEI   FQVQWSPHNE   TILASSGTDR   RLNVWDLSKI   350
351   GEEQSPEDAE   DGPPELLFIH   GGHTAKISDF   SWNPNEPWVI   CSVSEDNIMQ   400
401   VWQMAENIYN   DEDPEGSVDP   EGQGS       450

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
88_ASN SER gnomAD
chrX:16881125 		rs141907824
- 0.000239905 -
88_ASN SER 8.3kJPN
chrX:16881125 		rs141907824
- 0.0001 -
210_VAL ILE 8.3kJPN
chr1:33134600 		rs34196891
- 0.0023 -
216_ILE SER 8.3kJPN
chrX:16871919 		-
- 0.0001 -
261_ASN SER 8.3kJPN
chr1:33134852 		rs547545024
- 0.0001 -
385_ASN SER gnomAD
chrX:16864009 		rs777632567
- 0.000137063 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.