PDB ID 2UZ8     CHAIN A
Protein name EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1
Uniprot Accession O43324
The number of similar proteins 6
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2UZ8 (CHAIN: A)
1 Monomeric state
2 P56192  
3 P07814  
4 P07814   P14868   Q13155   P56192  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   AAAAELSLLE   KSLGLSKGNK   YSAQGERQIP   VLQTNNGPSL   XGLTTIAAHL   50
51   VKQANKEYLL   GSTAEEKAXV   QQWLEYRVTQ   VDGHSSKNDI   HTLLXDLNSY   100
101   LEDKVYLTGY   NFTLADILLY   YGLHRFIVDL   TVQEKEKYLN   VSRWFCHIQH   150
151   YPGIRQHLSS   VVFIKNRLYT   NSH       200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
56_ASN SER gnomAD
chr6:8097621 		rs148166016
- 0.00054484 -
56_ASN SER 8.3kJPN
chr6:8097621 		rs148166016
- 0.0032 -
70_ILE VAL 8.3kJPN
chr6:8097580 		-
- 0.0001 -
95_LEU VAL 8.3kJPN
chr6:8097505 		-
- 0.0001 -
118_ILE THR gnomAD
chr6:8090450 		rs539867069
- 0.000112529 -
124_LEU VAL 8.3kJPN
chr6:8090433 		-
- 0.0002 -
157_GLN TER 8.3kJPN
chr6:8080179 		-
- 0.0001 -
161_SER ASN 8.3kJPN
chr6:8080166 		rs192943830
- 0.0005 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.