| PDB ID | 2QTS
|
CHAIN | A |
|---|---|---|---|
| Protein name | Acid-sensing ion channel | ||
| Uniprot Accession | Q1XA76 | ||
| The number of similar proteins | 40 | ||
| The number of binding states | 5 | ||
| The number of binding partners | 4 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 2QTS (CHAIN: A) | |
| 1 |
Q1XA76
Q1XA76
|
| 2 | Monomeric state |
| 3 |
P60514
|
| 4 |
G9I930
G9I929
|
| 5 |
Q1XA76
Q1XA76
P60514
P60514
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 49_LEU | VAL |
8.3kJPN chr12:50452691 - |
- | 0.0001 | - | - | |
| 65_ARG | HIS |
8.3kJPN chr12:50452740 - |
- | 0.0001 | - | - | |
| 79_ASP | ASN |
8.3kJPN chr12:50452781 rs780194390 |
- | 0.0001 | - | - | |
| 91_VAL | ILE |
8.3kJPN chr12:50452817 rs1306904297 |
- | 0.0001 | - | - | |
| 98_GLU | LYS |
8.3kJPN chr12:50452838 rs773503565 |
- | 0.0001 | - | - | |
| 151_LYS | GLU |
8.3kJPN chr12:50453627 - |
- | 0.0001 | - | - | |
| 156_ARG | HIS |
8.3kJPN chr12:50453643 rs766103987 |
- | 0.0001 | - | - | |
| 197_THR | MET |
8.3kJPN chr12:50471024 rs755008406 |
- | 0.0001 | - | - | |
| 201_GLY | SER |
8.3kJPN chr12:50471035 rs746113466 |
- | 0.0001 | - | - | |
| 213_GLY | ASP |
8.3kJPN chr12:50471072 rs765919956 |
- | 0.0001 | - | - | |
| 215_THR | MET |
8.3kJPN chr12:50471078 rs373616682 |
- | 0.0001 | - | - | |
| 302_ASP | ASN |
8.3kJPN chr12:50472273 rs774054780 |
- | 0.0001 | - | - | |
| 315_THR | MET |
8.3kJPN chr12:50472313 rs200645931 |
- | 0.0004 | - | - | |
| 361_VAL | MET |
gnomAD chr12:50473717 rs199923697 |
- | 0.000203564 | - | - | |
| 410_PHE | VAL |
8.3kJPN chr12:50474306 - |
- | 0.0001 | - | - |