PDB ID 2QL5     CHAIN A
Protein name Caspase-7
Uniprot Accession P55210
The number of similar proteins 48
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
2QL5 (CHAIN: A)
1 P55210   P55210   P55210  
2 P55210  
3 P55210   4JB8  
4 P55210   P55210   P55210   4LSZ  
5 P55210   P55210   P55210   P98170  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   AKPDRSSFVP   SLFSKKKKNV   TMRSIKTTRD   RVPTYQYNMN   FEKLGKCIII   50
51   NNKNFDKVTG   MGVRNGTDKD   AEALFKCFRS   LGFDVIVYND   CSCAKMQDLL   100
101   KKASEEDHTN   AACFACILLS   HGEENVIYGK   DGVTPIKDLT   AHFRGDRCKT   150
151   LLEKPKLFFI   QACRGTELDD   GIQ       200

Variants

Residue AA Source /
dbSNP
Clinical
Significance
Allele
Frequency
(> 0.0001)
AlphaMissense
pathogenicity
Disease name
62_MET LEU 8.3kJPN
chr10:115480864
-
- 0.0001 0.2864 -
75_ASN LYS 8.3kJPN
chr10:115480905
-
- 0.0001 0.9923 -
86_VAL ILE gnomAD
chr10:115481418
rs115183028
- 0.000111349 0.07 -
89_GLY ARG 8.3kJPN
chr10:115481427
rs757905204
- 0.0001 0.9916 -
96_ALA VAL 8.3kJPN
chr10:115481449
rs1482095638
- 0.0001 0.1598 -
98_PHE LEU 8.3kJPN
chr10:115481454
rs1383138083
- 0.0001 0.4693 -
102_ARG GLN gnomAD
chr10:115481467
rs146796754
- 0.000198826 0.0634 -
121_ASP GLU 8.3kJPN
chr10:115481525
rs368309877
- 0.0001 0.0798 -
136_CYS PHE 8.3kJPN
chr10:115485151
rs1018566256
- 0.0001 0.8246 -
169_ASP TYR 8.3kJPN
chr10:115485249
-
- 0.0001 0.8811 -
171_CYS SER gnomAD
chr10:115485256
rs201040237
- 0.000179947 0.954 -
181_PHE LEU gnomAD
chr10:115485285
rs141266925
- 0.00426735 0.9939 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.