PDB ID 2NYY     CHAIN A
Protein name Botulinum neurotoxin type A
Uniprot Accession P10845
The number of similar proteins 7
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
2NYY (CHAIN: A)
1 2NZ9   2NZ9  
2 Monomeric state
3 Q45914  
4 3V0A   Q45914  
5 9EA9   9EA9   Q8KHU9   Q45914  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   PFVNKQFNYK   DPVNGVDIAY   IKIPNVGQMQ   PVKAFKIHNK   IWVIPERDTF   50
51   TNPEEGDLNP   PPEAKQVPVS   YYDSTYLSTD   NEKDNYLKGV   TKLFERIYST   100
101   DLGRMLLTSI   VRGIPFWGGS   TIDTELKVID   TNCINVIQPD   GSYRSEELNL   150
151   VIIGPSADII   QFECKSFGHE   VLNLTRNGYG   STQYIRFSPD   FTFGFEESLE   200
201   VDTNPLLGAG   KFATDPAVTL   AHELIHAGHR   LYGIAINPNR   VFKVNTNAYY   250
251   EMSGLEVSFE   ELRTFGGHDA   KFIDSLQENE   FRLYYYNKFK   DIASTLNKAK   300
301   SIVGTTASLQ   YMKNVFKEKY   LLSEDTSGKF   SVDKLKFDKL   YKMLTEIYTE   350
351   DNFVKFFKVL   NRKTYLNFDK   AVFKINIVPK   VNYTIYDGFN   LRNTNLAANF   400
401   NGQNTEINNM   NFTKLKNFTG   LFEFYKLLCV   RGIITSKTKS   LDKGYNKALN   450
451   DLCIKVNNWD   LFFSPSEDNF   TNDLNKGEEI   TSDTNIEAAE   ENISLDLIQQ   500
501   YYLTFNFDNE   PENISIENLS   SDIIGQLELM   PNIERFPNGK   KYELDKYTMF   550
551   HYLRAQEFEH   GKSRIALTNS   VNEALLNPSR   VYTFFSSDYV   KKVNKATEAA   600
601   MFLGWVEQLV   YDFTDETSEV   STTDKIADIT   IIIPYIGPAL   NIGNMLYKDD   650
651   FVGALIFSGA   VILLEFIPEI   AIPVLGTFAL   VSYIANKVLT   VQTIDNALSK   700
701   RNEKWDEVYK   YIVTNWLAKV   NTQIDLIRKK   MKEALENQAE   ATKAIINYQY   750
751   NQYTEEEKNN   INFNIDDLSS   KLNESINKAM   ININKFLNQC   SVSYLMNSMI   800
801   PYGVKRLEDF   DASLKDALLK   YIYDNRGTLI   GQVDRLKDKV   NNTLSTDIPF   850
851   QLSKYVDNQR   LLSTFTEYIK   NIINTSILNL   RYESNHLIDL   SRYASKINIG   900
901   SKVNFDPIDK   NQIQLFNLES   SKIEVILKNA   IVYNSMYENF   STSFWIRIPK   950
951   YFNSISLNNE   YTIINCMENN   SGWKVSLNYG   EIIWTLQDTQ   EIKQRVVFKY   1000
1001   SQMINISDYI   NRWIFVTITN   NRLNNSKIYI   NGRLIDQKPI   SNLGNIHASN   1050
1051   NIMFKLDGCR   DTHRYIWIKY   FNLFDKELNE   KEIKDLYDNQ   SNSGILKDFW   1100
1101   GDYLQYDKPY   YMLNLYDPNK   YVDVNNVGIR   GYMYLKGPRG   SVMTTNIYLN   1150
1151   SSLYRGTKFI   IKKYASGNKD   NIVRNNDRVY   INVVVKNKEY   RLATNASQAG   1200
1201   VEKILSALEI   PDVGNLSQVV   VMKSKNDQGI   TNKCKMNLQD   NNGNDIGFIG   1250
1251   FHQFNNIAKL   VASNWYNRQI   ERSSRTLGCS   WEFIPVDDGW   GERPL   1300

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.