| PDB ID | 2JCN
|
CHAIN | A |
|---|---|---|---|
| Protein name | BCL-2 HOMOLOGOUS ANTAGONIST/KILLER | ||
| PDB | 2JCN | ||
| The number of similar proteins | 44 | ||
| The number of binding states | 7 | ||
| The number of binding partners | 5 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 2JCN (CHAIN: A) | |
| 1 | Monomeric state |
| 2 |
P62979
|
| 3 |
Q16611
|
| 4 |
8UKY
8UKY
|
| 5 |
Q16611
7LK4
7LK4
|
| 6 |
Q16611
Q16611
Q16611
|
| 7 |
Q16611
7LK4
7LK4
7LK4
|
Downdload
Molecule viewer
|
Only interaction residues |
|
||||||||||
|
Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 28_ALA | VAL |
gnomAD chr6:33543693 rs4987115 |
- | 0.00477331 | - | - | |
| 28_ALA | VAL |
8.3kJPN chr6:33543693 rs4987115 |
- | 0.0045 | - | - | |
| 57_ASP | ASN |
8.3kJPN chr6:33543607 rs778549210 |
- | 0.0001 | - | - | |
| 76_ARG | TRP |
8.3kJPN chr6:33543199 rs766561404 |
- | 0.0001 | - | - | |
| 96_MET | ILE |
8.3kJPN chr6:33543137 rs1423887173 |
- | 0.0001 | - | - | |
| 101_GLN | PRO |
8.3kJPN chr6:33543123 - |
- | 0.0001 | - | - | |
| 103_THR | MET |
8.3kJPN chr6:33543117 rs373778311 |
- | 0.0001 | - | - | |
| 120_GLU | VAL |
gnomAD chr6:33541983 rs146926576 |
- | 0.000243807 | - | - | |
| 130_ALA | VAL |
8.3kJPN chr6:33541953 - |
- | 0.0001 | - | - | |
| 134_PHE | LEU |
8.3kJPN chr6:33541940 - |
- | 0.0003 | - | - | |
| 135_GLY | SER |
gnomAD chr6:33541939 rs548190187 |
- | 0.00012345 | - | - | |
| 137_ARG | LEU |
gnomAD chr6:33541932 rs748982597 |
- | 0.000107508 | - | - | |
| 137_ARG | HIS |
8.3kJPN chr6:33541932 rs748982597 |
- | 0.0002 | - | - | |
| 142_VAL | ILE |
gnomAD chr6:33541918 rs376712748 |
- | 0.000107464 | - | - | |
| 163_LEU | VAL |
gnomAD chr6:33541855 rs148199579 |
- | 0.000306309 | - | - | |
| 169_ARG | GLN |
8.3kJPN chr6:33541836 rs143054587 |
- | 0.0002 | - | - | |
| 169_ARG | TRP |
8.3kJPN chr6:33541837 rs773586210 |
- | 0.0001 | - | - |