| PDB ID | 2ICC
|
CHAIN | A |
|---|---|---|---|
| Protein name | V-set and immunoglobulin domain-containing protein 4 | ||
| Uniprot Accession | Q9Y279 | ||
| The number of similar proteins | 10 | ||
| The number of binding states | 4 | ||
| The number of binding partners | 4 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 2ICC (CHAIN: A) | |
| 1 | Monomeric state |
| 2 |
9EZV
|
| 3 |
P01024
P01024
|
| 4 |
P01024
P01024
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 1_ARG | CYS |
8.3kJPN chrX:65253670 rs201236670 |
- | 0.0025 | 0.0969 | - | |
| 33_VAL | LEU |
8.3kJPN chrX:65253574 rs755538009 |
- | 0.0021 | 0.2022 | - | |
| 39_VAL | GLY |
8.3kJPN chrX:65253555 rs199928988 |
- | 0.0008 | 0.3167 | - | |
| 45_PRO | THR |
gnomAD chrX:65253538 rs765225045 |
- | 0.00024679 | 0.0889 | - | |
| 66_ARG | HIS |
8.3kJPN chrX:65253474 rs202129863 |
- | 0.0002 | 0.1517 | - | |
| 73_VAL | PHE |
gnomAD chrX:65253454 rs41306131 |
- | 0.00566355 | 0.0956 | - | |
| 89_ARG | TRP |
VAR_049956
rs34581041 |
LB/B | - | 0.1008 | - | |
| 89_ARG | GLN |
gnomAD chrX:65253405 rs180937374 |
- | 0.000552214 | 0.0779 | - | |
| 89_ARG | TRP |
gnomAD chrX:65253406 rs34581041 |
- | 0.000995036 | 0.1008 | - | |
| 89_ARG | GLN |
8.3kJPN chrX:65253405 rs180937374 |
- | 0.0015 | 0.0779 | - | |
| 91_HIS | TYR |
8.3kJPN chrX:65253400 - |
- | 0.0001 | 0.0952 | - | |
| 98_TRP | ARG |
8.3kJPN chrX:65253379 - |
- | 0.0002 | 0.9692 | - | |
| 101_PRO | SER |
8.3kJPN chrX:65253370 - |
- | 0.0003 | 0.1099 | - | |
| 106_VAL | PHE |
gnomAD chrX:65253355 rs189022987 |
- | 0.000369933 | 0.1673 | - | |
| 106_VAL | PHE |
8.3kJPN chrX:65253355 rs189022987 |
- | 0.0232 | 0.1673 | - |