| PDB ID | 1YWH
|
CHAIN | A |
|---|---|---|---|
| Protein name | Urokinase plasminogen activator surface receptor | ||
| Uniprot Accession | Q9UMV0 | ||
| The number of similar proteins | 20 | ||
| The number of binding states | 8 | ||
| The number of binding partners | 5 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1YWH (CHAIN: A) | |
| 1 |
Q9UMV0
Q9UMV0
Q9UMV0
|
| 2 | Monomeric state |
| 3 |
P00749
|
| 4 |
Q03405
|
| 5 |
4QTI
4QTI
|
| 6 |
P04004
P00749
|
| 7 |
Q52L64
Q4V9V8
P00749
|
| 8 |
3BT2
3BT2
P04004
P00749
|
Downdload
Molecule viewer
|
Only interaction residues |
|
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|
Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 4_MET | ILE |
8.3kJPN chr19:44171821 - |
- | 0.0001 | - | - | |
| 16_GLU | LYS |
8.3kJPN chr19:44171787 - |
- | 0.0001 | - | - | |
| 20_GLY | VAL |
8.3kJPN chr19:44171774 rs1201479506 |
- | 0.0001 | - | - | |
| 22_ASP | HIS |
8.3kJPN chr19:44171769 rs778790349 |
- | 0.0001 | - | - | |
| 23_LEU | PHE |
8.3kJPN chr19:44171766 - |
- | 0.0001 | - | - | |
| 58_ARG | TRP |
8.3kJPN chr19:44169540 rs752525518 |
- | 0.0001 | - | - | |
| 64_THR | ALA |
gnomAD chr19:44169522 rs399145 |
- | 0.00823492 | - | - | |
| 72_GLY | GLU |
gnomAD chr19:44169497 rs150986089 |
- | 0.00100602 | - | - | |
| 74_ASP | ASN |
8.3kJPN chr19:44169492 - |
- | 0.0001 | - | - | |
| 89_ARG | GLN |
8.3kJPN chr19:44160771 rs753893509 |
- | 0.0001 | - | - | |
| 91_ARG | CYS |
8.3kJPN chr19:44160766 rs531645411 |
- | 0.0001 | - | - | |
| 95_CYS | ARG |
8.3kJPN chr19:44160754 - |
- | 0.0002 | - | - | |
| 109_ARG | TRP |
8.3kJPN chr19:44160712 rs772718099 |
- | 0.0001 | - | - | |
| 137_ARG | HIS |
gnomAD chr19:44159722 rs140011964 |
- | 0.00140113 | - | - | |
| 140_ASP | GLY |
8.3kJPN chr19:44159713 - |
- | 0.0001 | - | - | |
| 145_ARG | HIS |
8.3kJPN chr19:44159698 rs1157998153 |
- | 0.0001 | - | - | |
| 149_TYR | CYS |
8.3kJPN chr19:44159686 rs763744500 |
- | 0.0005 | - | - | |
| 157_ASN | SER |
gnomAD chr19:44159662 rs138306315 |
- | 0.000242579 | - | - | |
| 188_PRO | LEU |
gnomAD chr19:44156502 rs141507706 |
- | 0.000811385 | - | - | |
| 198_LYS | ARG |
gnomAD chr19:44156472 rs2302524 |
- | 0.163056 | - | - | |
| 198_LYS | ARG |
8.3kJPN chr19:44156472 rs2302524 |
- | 0.1112 | - | - | |
| 199_GLY | ARG |
gnomAD chr19:44156470 rs542078792 |
- | 0.000922546 | - | - | |
| 209_GLU | VAL |
8.3kJPN chr19:44156439 - |
- | 0.0001 | - | - | |
| 213_ILE | THR |
8.3kJPN chr19:44156427 - |
- | 0.0008 | - | - | |
| 230_GLU | LYS |
8.3kJPN chr19:44156377 rs757884538 |
- | 0.0002 | - | - | |
| 237_MET | THR |
8.3kJPN chr19:44153274 - |
- | 0.0001 | - | - | |
| 239_ARG | LYS |
8.3kJPN chr19:44153268 - |
- | 0.0001 | - | - | |
| 246_MET | VAL |
gnomAD chr19:44153248 rs138492321 |
- | 0.00361124 | - | - | |
| 255_ALA | THR |
8.3kJPN chr19:44153221 rs750492027 |
- | 0.0001 | - | - | |
| 259_ASN | LYS |
gnomAD chr19:44153207 rs4251921 |
- | 0.000866992 | - | - |