PDB ID 1XTF     CHAIN A
Protein name neurotoxin BoNT/A
GenBank ID 33321098
The number of similar proteins 61
The number of binding states 7
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1XTF (CHAIN: A)
1 Monomeric state
2 P60880  
3 8HKH  
4 A5HZZ9  
5 7LZP   7LZP   7LZP  
6 7L6V   7L6V   7L6V   7L6V   7L6V  
7 7M1H   7M1H   7M1H   7M1H   7M1H   7M1H  

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Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   PFVNKQFNYK   DPVNGVDIAY   IKIPNAGQMQ   PVKAFKIHNK   IWVIPERDTF   50
51   TNPEEGDLNP   PPEAKQVPVS   YYDSTYLSTD   NEKDNYLKGV   TKLFERIYST   100
101   DLGRMLLTSI   VRGIPFWGGS   TIDTELKVID   TNCINVIQPD   GSYRSEELNL   150
151   VIIGPSADII   QFECKSFGHE   VLNLTRNGYG   STQYIRFSPD   FTFGFEESLE   200
201   VDTNPLLGAG   KFATDPAVTL   AHQLIHAGHR   LYGIAINPNR   VFKVNTNAYY   250
251   EMSGLEVSFE   ELRTFGGHDA   KFIDSLQENE   FRLYYYNKFK   DIASTLNKAK   300
301   SIVGTTASLQ   YMKNVFKEKY   LLSEDTSGKF   SVDKLKFDKL   YKMLTEIYTE   350
351   DNFVKFFKVL   NRKTFLNFDK   AVFKINIVPK   VNYTIYDGFN   LRNTNLAANF   400
401   NGQNTEINNM   NFTKLKNFTP   GHHHHHH       450

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

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