PDB ID 1TEY     CHAIN A
Protein name ASF1 anti-silencing function 1 homolog A
Uniprot Accession Q9Y294
The number of similar proteins 29
The number of binding states 8
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1TEY (CHAIN: A)
1 Monomeric state
2 Q9Y294  
3 P54198  
4 P21675  
5 Q9Y294   Q9Y294  
6 P62805   P68431  
7 Q9Y294   Q9Y294   Q9Y294  
8 P49321   P62805   P68431  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   GAMAKVQVNN   VVVLDNPSPF   YNPFQFEITF   ECIEDLSEDL   EWKIIYVGSA   50
51   ESEEYDQVLD   SVLVGPVPAG   RHMFVFQADA   PNPGLIPDAD   AVGVTVVLIT   100
101   CTYRGQEFIR   VGYYVNNEYT   ETELRENPPV   KPDFSKLQRN   ILASNPRVTR   150
151   FHINWEDN           200

Variants

Residue AA Source /
dbSNP
Clinical
Significance
Allele
Frequency
(> 0.0001)
AlphaMissense
pathogenicity
Disease name
21_PRO ALA 8.3kJPN
chr19:14247208
-
- 0.0005 0.6367 -
33_ASP HIS 8.3kJPN
chr6:119215674
-
- 0.0001 0.9318 -
50_SER ASN 8.3kJPN
chr19:14237010
-
- 0.0001 0.7578 -
64_PRO SER 8.3kJPN
chr19:14236969
-
- 0.0001 0.9982 -
89_ALA SER 8.3kJPN
chr6:119226856
-
- 0.0001 0.6397 -
111_TYR HIS 8.3kJPN
chr19:14232415
-
- 0.0001 0.9998 -
113_VAL ILE 8.3kJPN
chr19:14232409
rs745941748
- 0.0001 0.375 -
130_PRO ALA gnomAD
chr19:14232358
rs187314288
- 0.000303139 0.7487 -
137_ARG GLN 8.3kJPN
chr19:14231470
rs745397948
- 0.0001 0.9992 -
142_SER LEU 8.3kJPN
chr19:14231455
rs758936633
- 0.0001 0.7581 -
150_HIS ARG gnomAD
chr19:14231431
rs151302500
- 0.000123365 0.6823 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.