PDB ID 1OZN     CHAIN A
Protein name Reticulon 4 receptor
Uniprot Accession Q9BZR6
The number of similar proteins 21
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1OZN (CHAIN: A)
1 Monomeric state
2 Q99PI8  
3 Q3UHD1  
4 3KJ4   3KJ4  
5 Q99PI8   Q99PI8   Q99PI8  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   PCPGACVCYN   EPKVTTSCPQ   QGLQAVPVGI   PAASQRIFLH   GNRISHVPAA   50
51   SFRACRNLTI   LWLHSNVLAR   IDAAAFTGLA   LLEQLDLSDN   AQLRSVDPAT   100
101   FHGLGRLHTL   HLDRCGLQEL   GPGLFRGLAA   LQYLYLQDNA   LQALPDDTFR   150
151   DLGNLTHLFL   HGNRISSVPE   RAFRGLHSLD   RLLLHQNRVA   HVHPHAFRDL   200
201   GRLMTLYLFA   NNLSALPTEA   LAPLRALQYL   RLNDNPWVCD   CRARPLWAWL   250
251   QKFRGSSSEV   PCSLPQRLAG   RDLKRLAAND   LQGCA     300

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
39_VAL MET 8.3kJPN
chr22:20230541 		-
- 0.0001 -
53_VAL MET VAR_079224 rs145292678
LB/B - -
53_VAL LEU 8.3kJPN
chr22:20230499 		-
- 0.0001 -
66_GLY SER gnomAD
chr22:20230460 		rs56235791
- 0.000256402 -
68_ARG HIS VAR_079225 rs145773589
LB/B - -
68_ARG HIS gnomAD
chr22:20230453 		rs145773589
- 0.000130768 -
68_ARG HIS 8.3kJPN
chr22:20230453 		rs145773589
- 0.0025 -
116_ALA SER 8.3kJPN
chr22:20230310 		rs775520463
- 0.0001 -
119_ARG TRP VAR_079154 rs74315508
LP/P - Schizophrenia (SCZD) [MIM:181500]
119_ARG TRP gnomAD
chr22:20230301 		rs74315508
- 0.000352378 -
124_ALA PRO 8.3kJPN
chr22:20230286 		-
- 0.0001 -
131_ARG HIS gnomAD
chr22:20230264 		rs144276737
- 0.000146294 -
131_ARG HIS 8.3kJPN
chr22:20230264 		rs144276737
- 0.0003 -
141_GLY SER VAR_079226 rs760855779
LB/B - -
147_PRO LEU 8.3kJPN
chr22:20230216 		rs113041746
- 0.0001 -
149_LEU MET gnomAD
chr22:20230211 		rs375571554
- 0.000105874 -
172_ASP GLU gnomAD
chr22:20230140 		rs117955118
- 0.000103915 -
172_ASP GLU 8.3kJPN
chr22:20230140 		rs117955118
- 0.0009 -
177_LEU PRO 8.3kJPN
chr22:20230126 		-
- 0.0001 -
184_PHE LEU 8.3kJPN
chr22:20230106 		-
- 0.0001 -
187_GLY SER gnomAD
chr22:20230097 		rs770160195
- 0.000115757 -
196_ARG HIS VAR_079155 rs74315509
LP/P - Schizophrenia (SCZD) [MIM:181500]
227_ARG CYS VAR_079227 rs754793885
US - Schizophrenia (SCZD) [MIM:181500]
227_ARG HIS VAR_079228 rs576939822
LB/B - -
227_ARG HIS 8.3kJPN
chr22:20229976 		rs576939822
- 0.0001 -
259_ASP ASN VAR_079229 rs3747073
LB/B - -
259_ASP ASN 8.3kJPN
chr22:20229881 		rs3747073
- 0.004 -
263_VAL MET VAR_079230 rs752810777
LB/B - -
263_VAL MET 8.3kJPN
chr22:20229869 		rs752810777
- 0.0001 -
267_ARG GLN 8.3kJPN
chr22:20229856 		rs1213179762
- 0.0001 -
269_ARG HIS gnomAD
chr22:20229850 		rs548639274
- 0.000105527 -
279_ARG HIS gnomAD
chr22:20229820 		rs144550064
- 0.000151387 -
292_ARG HIS VAR_079231 rs1432033565
LP/P - Schizophrenia (SCZD) [MIM:181500]
292_ARG HIS 8.3kJPN
chr22:20229781 		rs1432033565
- 0.0002 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.