PiSITE

PDB ID	1L6E	CHAIN	A
Protein name	cAMP-dependent protein kinase Type II-alpha regulatory chain
Uniprot Accession	P12367
The number of similar proteins	28
The number of binding states	8
The number of binding partners	5

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The number of binding partners

Group

Binding state	Binding partners
	1L6E (CHAIN: A)
1	P12367
2	P12368 O43572
3	2IZY 2IZY
4	P13861 Q06455
5	P13861 O43687
6	P12368 Q5T2W1 O43572
7	2IZY 2IZY 2IZY
8	2IZY 2IZY 2IZY 2IZY

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Molecule viewer

Only interaction residues

#binding
partners

	4
	3
	2
	1
	0

Sequence information

1

HMGHIQIPPG

LTELLQGYTV

EVLRQQPPDL

VDFAVEYFTR

LREARR

50

Variants

	Residue	AA	Source / dbSNP	Clinical Significance	Allele Frequency (> 0.0001)	AlphaMissense pathogenicity	Disease name
	24_ARG	TER	8.3kJPN chr3:48884963 -	-	0.0001	-	-
	26_GLN	HIS	8.3kJPN chr3:48884955 -	-	0.0013	-	-
	30_LEU	PHE	8.3kJPN chr3:48884945 -	-	0.0001	-	-

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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364