PDB ID 1K96     CHAIN A
Protein name S100A6
Uniprot Accession P06703
The number of similar proteins 19
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
1K96 (CHAIN: A)
1 Monomeric state
2 P06703  
3 Q15109  
4 P06703   Q15109   Q15109  
5 P30801   Q9CXW3   Q9CXW3  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MACPLDQAIG   LLVAIFHKYS   GREGDKHTLS   KKELKELIQK   ELTIGSKLQD   50
51   AEIARLMEDL   DRNKDQEVNF   QEYVTFLGAL   ALIYNEALKG     100

Variants

Residue AA Source /
dbSNP
Clinical
Significance
Allele
Frequency
(> 0.0001)
AlphaMissense
pathogenicity
Disease name
2_ALA THR gnomAD
chr1:153507812
rs147817499
- 0.000199138 0.1233 -
3_CYS ARG gnomAD
chr1:153507809
rs146161869
- 0.00175179 0.2337 -
27_HIS ARG VAR_011982
rs11974
LB/B - 0.1374 -
36_GLU GLN gnomAD
chr1:153507710
rs11555944
- 0.000119324 0.2135 -
37_LEU VAL 8.3kJPN
chr1:153507707
-
- 0.0001 0.5406 -
47_LYS ASN 8.3kJPN
chr1:153507304
-
- 0.0001 0.3414 -
62_ARG TRP gnomAD
chr1:153507261
rs201211621
- 0.000258849 0.2138 -
62_ARG TRP 8.3kJPN
chr1:153507261
rs201211621
- - 0.2138 -
69_ASN SER VAR_011983
rs1802581
LB/B - 0.1174 -
83_ILE THR VAR_011984
rs1802582
LB/B - 0.6865 -
90_GLY ASP VAR_029281
rs2228293
LB/B - 0.1775 -
90_GLY ASP gnomAD
chr1:153507176
rs2228293
- 0.0019398 0.1775 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.