| PDB ID | 1JV2
|
CHAIN | A |
|---|---|---|---|
| Protein name | INTEGRIN, ALPHA V | ||
| GenBank ID | 14743192 | ||
| The number of similar proteins | 15 | ||
| The number of binding states | 4 | ||
| The number of binding partners | 5 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1JV2 (CHAIN: A) | |
| 1 |
P05106
|
| 2 |
P02751
P05106
|
| 3 |
P05106
6MSL
|
| 4 |
P05106
4O02
4O02
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 14_PRO | ARG |
8.3kJPN chr2:187455196 rs748486456 |
- | 0.0002 | - | - | |
| 26_PHE | LEU |
gnomAD chr2:187455233 rs201076250 |
- | 0.000193425 | - | - | |
| 44_ASN | THR |
8.3kJPN chr2:187466783 - |
- | 0.0001 | - | - | |
| 58_LYS | ARG |
8.3kJPN chr2:187466825 rs754337745 |
- | 0.0001 | - | - | |
| 60_ASP | ALA |
8.3kJPN chr2:187466831 - |
- | 0.0001 | - | - | |
| 64_THR | PRO |
gnomAD chr2:187466842 rs750649139 |
- | 0.00326009 | - | - | |
| 66_ARG | GLN |
gnomAD chr2:187466849 rs201909609 |
- | 0.000124443 | - | - | |
| 66_ARG | TRP |
8.3kJPN chr2:187466848 rs200516634 |
- | 0.0001 | - | - | |
| 66_ARG | GLN |
8.3kJPN chr2:187466849 rs201909609 |
- | 0.0004 | - | - | |
| 77_ASN | ASP |
8.3kJPN chr2:187487068 rs1168435795 |
- | 0.0001 | - | - | |
| 79_ASP | GLU |
gnomAD chr2:187487076 rs200368244 |
- | 0.000123465 | - | - | |
| 108_CYS | TYR |
8.3kJPN chr2:187490204 - |
- | 0.0001 | - | - | |
| 113_HIS | ARG |
8.3kJPN chr2:187490219 rs1336656683 |
- | 0.0001 | - | - | |
| 192_VAL | ILE |
8.3kJPN chr2:187500841 rs200647242 |
- | 0.0004 | - | - | |
| 211_ARG | GLN |
gnomAD chr2:187500899 rs376680231 |
- | 0.000108022 | - | - | |
| 211_ARG | TRP |
8.3kJPN chr2:187500898 rs372449821 |
- | 0.0001 | - | - | |
| 231_PHE | ILE |
8.3kJPN chr2:187501815 - |
- | 0.0001 | - | - | |
| 232_ASN | SER |
gnomAD chr2:187501819 rs184114187 |
- | 0.000159086 | - | - | |
| 250_LEU | SER |
8.3kJPN chr2:187503040 - |
- | 0.0001 | - | - | |
| 255_ILE | MET |
8.3kJPN chr2:187503144 - |
- | 0.0001 | - | - | |
| 328_THR | MET |
8.3kJPN chr2:187506229 rs375790223 |
- | 0.0001 | - | - | |
| 359_ALA | VAL |
gnomAD chr2:187511419 rs145167954 |
- | 0.000178155 | - | - | |
| 373_VAL | ILE |
gnomAD chr2:187511460 rs569411702 |
- | 0.000196765 | - | - | |
| 375_ILE | VAL |
gnomAD chr2:187511466 rs3738918 |
- | 0.0248177 | - | - | |
| 375_ILE | VAL |
8.3kJPN chr2:187511466 rs3738918 |
- | 0.0594 | - | - | |
| 408_MET | VAL |
8.3kJPN chr2:187511565 - |
- | 0.0004 | - | - | |
| 414_ILE | THR |
8.3kJPN chr2:187511584 rs757308379 |
- | 0.0001 | - | - | |
| 414_ILE | MET |
8.3kJPN chr2:187511585 - |
- | 0.0001 | - | - | |
| 423_ILE | THR |
8.3kJPN chr2:187514573 - |
- | 0.0001 | - | - | |
| 431_ARG | LEU |
gnomAD chr2:187514597 rs750343053 |
- | 0.000569832 | - | - | |
| 441_ILE | THR |
8.3kJPN chr2:187516723 rs201241523 |
- | 0.0002 | - | - | |
| 444_ASN | SER |
8.3kJPN chr2:187516732 rs755750941 |
- | 0.0002 | - | - | |
| 452_SER | GLY |
8.3kJPN chr2:187516755 - |
- | 0.0004 | - | - | |
| 453_ILE | ASN |
8.3kJPN chr2:187516759 - |
- | 0.0001 | - | - | |
| 458_ASN | SER |
gnomAD chr2:187516774 rs200705825 |
- | 0.000115445 | - | - | |
| 465_GLY | ALA |
gnomAD chr2:187516795 rs147403786 |
- | 0.000657533 | - | - | |
| 465_GLY | TER |
8.3kJPN chr2:187516794 - |
- | 0.0001 | - | - | |
| 506_GLY | ARG |
8.3kJPN chr2:187521015 - |
- | 0.0001 | - | - | |
| 518_SER | ALA |
gnomAD chr2:187521051 rs2230615 |
- | 0.000203823 | - | - | |
| 520_SER | GLY |
8.3kJPN chr2:187521057 rs200088164 |
- | 0.0001 | - | - | |
| 522_SER | PHE |
gnomAD chr2:187521064 rs146565475 |
- | 0.000100032 | - | - | |
| 531_GLY | VAL |
8.3kJPN chr2:187521091 rs185792013 |
- | 0.0001 | - | - | |
| 540_ALA | VAL |
gnomAD chr2:187521118 rs199670325 |
- | 0.000190019 | - | - | |
| 548_PHE | LEU |
8.3kJPN chr2:187523779 - |
- | 0.0001 | - | - | |
| 577_ILE | VAL |
8.3kJPN chr2:187523864 - |
- | 0.0001 | - | - | |
| 582_THR | MET |
gnomAD chr2:187523880 rs150474737 |
- | 0.000137055 | - | - | |
| 613_ASP | ASN |
8.3kJPN chr2:187529222 - |
- | 0.0002 | - | - | |
| 613_ASP | GLU |
8.3kJPN chr2:187529224 - |
- | 0.0002 | - | - | |
| 619_ILE | THR |
8.3kJPN chr2:187529241 rs200809220 |
- | 0.0001 | - | - | |
| 622_ASP | HIS |
8.3kJPN chr2:187529249 - |
- | 0.0001 | - | - | |
| 655_GLY | ARG |
gnomAD chr2:187529348 rs200130364 |
- | 0.000155161 | - | - | |
| 677_ARG | HIS |
8.3kJPN chr2:187529899 rs554897868 |
- | 0.0001 | - | - | |
| 680_VAL | ILE |
8.3kJPN chr2:187529907 rs752134103 |
- | 0.0005 | - | - | |
| 721_ASN | ILE |
8.3kJPN chr2:187531882 rs772750590 |
- | 0.0003 | - | - | |
| 736_LEU | PHE |
8.3kJPN chr2:187531926 - |
- | 0.0001 | - | - | |
| 753_VAL | ILE |
gnomAD chr2:187532417 rs2230616 |
- | 0.998257 | - | - | |
| 766_PRO | THR |
gnomAD chr2:187532456 rs201122594 |
- | 0.000322319 | - | - | |
| 772_VAL | ILE |
8.3kJPN chr2:187532474 rs193173970 |
- | 0.0002 | - | - | |
| 780_TYR | CYS |
8.3kJPN chr2:187532499 rs756998836 |
- | 0.0001 | - | - | |
| 785_ASN | SER |
gnomAD chr2:187533499 rs61757099 |
- | 0.000268264 | - | - | |
| 800_PRO | ARG |
8.3kJPN chr2:187533544 rs767980859 |
- | 0.0005 | - | - | |
| 803_TYR | CYS |
8.3kJPN chr2:187533553 rs199789114 |
- | 0.0001 | - | - | |
| 877_ALA | SER |
8.3kJPN chr2:187540343 - |
- | 0.0001 | - | - | |
| 894_SER | ASN |
gnomAD chr2:187540395 rs56316527 |
- | 0.00138018 | - | - | |
| 899_VAL | ILE |
gnomAD chr2:187540409 rs146319338 |
- | 0.000111382 | - | - | |
| 919_SER | ALA |
8.3kJPN chr2:187540571 rs202153093 |
- | 0.0005 | - | - | |
| 934_LYS | ASN |
8.3kJPN chr2:187540618 - |
- | 0.0005 | - | - | |
| 945_THR | ALA |
8.3kJPN chr2:187540649 - |
- | 0.0001 | - | - |