PDB ID 1JT3     CHAIN A
Protein name acidic fibroblast growth factor
Uniprot Accession P05230
The number of similar proteins 108
The number of binding states 7
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1JT3 (CHAIN: A)
1 Monomeric state
2 P22607  
3 P21579  
4 Q99584  
5 P11362   P11362  
6 P21579   Q99584  
7 P21802   P21802  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   HHHHHHFNLP   PGNYKKPKLL   YCSNGGHFLR   ILPDGTVDGT   RDRSDQHIQL   50
51   QLSAESVGEV   YIKSTETGQY   LAMDTDGLVY   GSQTPNEECL   FLERLEENHY   100
101   NTYISKKHAE   KNWFVGLKKN   GSCKRGPRTH   YGQKAILFLP   LPVSSD   150

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
6_GLY GLU VAR_021357
rs17223632
LB/B - 0.1303 -
6_GLY GLU gnomAD
chr5:141993631
rs17223632
- 0.00451744 0.1303 -
10_LYS ASN 8.3kJPN
chr5:141993618
rs770703997
- 0.0001 0.205 -
60_GLU LYS gnomAD
chr5:141980317
rs148224095
- 0.000123467 0.0892 -
122_ARG GLN gnomAD
chr5:141974913
rs146745580
- 0.000135486 0.1921 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.