PDB ID 1I1B     CHAIN A
Protein name INTERLEUKIN-1 BETA
Uniprot Accession P01584
The number of similar proteins 58
The number of binding states 6
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1I1B (CHAIN: A)
1 Monomeric state
2 P14778  
3 2KH2  
4 5MVZ   5MVZ  
5 Q9NPH3   P14778  
6 4G6M   4G6M  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   APVRSLNCTL   RDSQQKSLVM   SGPYELKALH   LQGQDMEQQV   VFSMSFVQGE   50
51   ESNDKIPVAL   GLKEKNLYLS   CVLKDDKPTL   QLESVDPKNY   PKKKMEKRFV   100
101   FNKIEINNKL   EFESAQFPNW   YISTSQAENM   PVFLGGTKGG   QDITDFTMQF   150
151   VSS           200

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
25_GLU ASN VAR_073951
rs144640380
LB/B - 0.663 -
39_GLN HIS 8.3kJPN
chr2:113590240
-
- 0.0001 0.775 -
112_PHE LEU 8.3kJPN
chr2:113588064
-
- 0.0001 0.9939 -
122_ILE VAL gnomAD
chr2:113588036
rs553523253
- 0.00010736 0.3479 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.