PDB ID 1EMR     CHAIN A
Protein name LEUKEMIA INHIBITORY FACTOR
Uniprot Accession P15018
The number of similar proteins 4
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1EMR (CHAIN: A)
1 Monomeric state
2 P40189  
3 P42703  
4 7N0A   7N0A  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   LMNQIRSQLA   QLNGSANALF   ILYYTAQGEP   FPNNLEKLCG   PNVTDFPPFH   50
51   ANGTEKAKLV   ELYRIVVYLG   TSLGNITRDQ   KILNPSALSL   HSKLNATADI   100
101   LRGLLSNVLC   RLCSKYHVGH   VDVTYGPDTS   GKDVFQKKKL   GCQLLGKYKQ   150
151   VISVLAQAF           200

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
61_CYS ARG 8.3kJPN
chr22:30640005 		-
- 0.0001 -
65_VAL MET gnomAD
chr22:30639993 		rs41281637
- 0.00521244 -
65_VAL MET 8.3kJPN
chr22:30639993 		rs41281637
- 0.0001 -
73_ALA THR gnomAD
chr22:30639969 		rs114631508
- 0.00477707 -
90_TYR CYS 8.3kJPN
chr22:30639917 		rs1424596709
- 0.0001 -
114_SER GLY 8.3kJPN
chr22:30639846 		-
- 0.0002 -
118_ALA THR gnomAD
chr22:30639834 		rs114169546
- 0.00138012 -
133_ARG CYS 8.3kJPN
chr22:30639789 		rs533306784
- 0.0001 -
148_GLY SER 8.3kJPN
chr22:30639744 		rs146996425
- 0.0005 -
152_SER LEU 8.3kJPN
chr22:30639731 		rs755503585
- 0.0001 -
154_LYS MET 8.3kJPN
chr22:30639725 		-
- 0.0001 -
169_LYS ARG 8.3kJPN
chr22:30639680 		rs1487093302
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.