PDB ID 1E9H     CHAIN A
Protein name CELL DIVISION PROTEIN KINASE 2
PDB 1E9H
The number of similar proteins 456
The number of binding states 13
The number of binding partners 10

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1E9H (CHAIN: A)
1 P20248  
2 Monomeric state
3 P24864  
4 P61024  
5 P89883  
6 Q5MJ70  
7 Q16667  
8 P20248   Q99741  
9 P20248   P46527  
10 P24941   P20248  
11 P46527   Q5MJ70  
12 Q5MJ70   O94901  
13 P24941   P20248   P20248  

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Only interaction residues
#binding
partners
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   SMENFQKVEK   IGEGTYGVVY   KARNKLTGEV   VALKKIRLDT   ETEGVPSTAI   50
51   REISLLKELN   HPNIVKLLDV   IHTENKLYLV   FEFLHQDLKK   FMDASALTGI   100
101   PLPLIKSYLF   QLLQGLAFCH   SHRVLHRDLK   PQNLLINTEG   AIKLADFGLA   150
151   RAFGVPVRTY   XHEVVTLWYR   APEILLGCKY   YSTAVDIWSL   GCIFAEMVTR   200
201   RALFPGDSEI   DQLFRIFRTL   GTPDEVVWPG   VTSMPDYKPS   FPKWARQDFS   250
251   KVVPPLDEDG   RSLLSQMLHY   DPNKRISAKA   ALAHPFFQDV   TKPVPHL   300

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
3_ASN LYS gnomAD
chr12:56360801 		rs139342756
- 0.000510365 -
77_TYR HIS 8.3kJPN
chr12:56361867 		rs1325392225
- 0.0001 -
109_PHE LEU 8.3kJPN
chr12:56362573 		rs756703184
- 0.0006 -
200_ARG GLN 8.3kJPN
chr12:56364838 		rs763512696
- 0.0001 -
210_ASP ALA 8.3kJPN
chr12:56364868 		-
- 0.0001 -
214_ARG GLN 8.3kJPN
chr12:56364880 		-
- 0.0001 -
231_THR ASN 8.3kJPN
chr12:56364931 		-
- 0.0001 -
245_ARG GLN gnomAD
chr12:56364973 		rs144092294
- 0.000222668 -
245_ARG TRP 8.3kJPN
chr12:56364972 		rs868674487
- 0.0002 -
245_ARG GLN 8.3kJPN
chr12:56364973 		rs144092294
- 0.0019 -
255_LEU VAL 8.3kJPN
chr12:56365002 		rs1359177454
- 0.0003 -
256_ASP ASN 8.3kJPN
chr12:56365005 		-
- 0.0001 -
260_ARG GLN 8.3kJPN
chr12:56365018 		rs774683147
- 0.0001 -
270_ASP ASN 8.3kJPN
chr12:56365320 		rs759820038
- 0.0001 -
290_THR SER gnomAD
chr12:56365381 		rs2069413
- 0.00232636 -
290_THR SER 8.3kJPN
chr12:56365381 		rs2069413
- 0.0069 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.