| PDB ID | 1CX8
|
CHAIN | A |
|---|---|---|---|
| Protein name | TRANSFERRIN RECEPTOR PROTEIN | ||
| Uniprot Accession | P02786 | ||
| The number of similar proteins | 16 | ||
| The number of binding states | 8 | ||
| The number of binding partners | 6 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1CX8 (CHAIN: A) | |
| 1 |
P02786
|
| 2 |
P02787
|
| 3 |
Q8AZ57
|
| 4 |
6OKD
|
| 5 |
6WRV
|
| 6 |
P02786
6WRW
|
| 7 |
P02786
Q30201
Q30201
|
| 8 |
P02786
6WRV
6WRV
|
Downdload
Molecule viewer
|
Only interaction residues |
|
||||||||||||
|
Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 132_SER | LEU |
8.3kJPN chr3:195800840 rs370784605 |
- | 0.0001 | 0.1017 | - | |
| 142_GLY | SER |
gnomAD chr3:195800811 rs3817672 |
- | 0.449417 | - | - | |
| 142_GLY | SER |
8.3kJPN chr3:195800811 rs3817672 |
- | 0.2078 | - | - | |
| 160_GLN | ARG |
8.3kJPN chr3:195798979 - |
- | 0.0001 | 0.077 | - | |
| 166_ALA | VAL |
8.3kJPN chr3:195798961 rs771569167 |
- | 0.0001 | 0.4873 | - | |
| 183_ARG | HIS |
8.3kJPN chr3:195798910 rs778329855 |
- | 0.0002 | 0.0664 | - | |
| 212_LEU | VAL |
VAR_051806
rs41301381 |
LB/B | - | 0.0659 | - | |
| 212_LEU | VAL |
gnomAD chr3:195798320 rs41301381 |
- | 0.00196839 | 0.0659 | - | |
| 212_LEU | VAL |
8.3kJPN chr3:195798320 rs41301381 |
- | 0.0254 | 0.0659 | - | |
| 221_ALA | VAL |
8.3kJPN chr3:195798292 rs754768415 |
- | 0.0002 | 0.6769 | - | |
| 230_GLY | SER |
8.3kJPN chr3:195796439 - |
- | 0.0001 | 0.2858 | - | |
| 248_THR | ILE |
8.3kJPN chr3:195796384 rs762642181 |
- | 0.0011 | 0.0736 | - | |
| 277_ILE | VAL |
8.3kJPN chr3:195794974 rs533268185 |
- | 0.0001 | 0.0656 | - | |
| 293_ALA | THR |
8.3kJPN chr3:195794926 rs541398971 |
- | 0.0001 | 0.0952 | - | |
| 296_SER | PRO |
8.3kJPN chr3:195794917 rs1310686971 |
- | 0.0001 | 0.0502 | - | |
| 303_LEU | ARG |
8.3kJPN chr3:195794521 - |
- | 0.0002 | 0.1404 | - | |
| 337_ILE | VAL |
gnomAD chr3:195794420 rs41295849 |
- | 0.000437975 | 0.0964 | - | |
| 337_ILE | VAL |
8.3kJPN chr3:195794420 rs41295849 |
- | 0.0004 | 0.0964 | - | |
| 352_ASP | GLY |
gnomAD chr3:195792457 rs140316777 |
- | 0.00033598 | 0.0869 | - | |
| 362_THR | ALA |
8.3kJPN chr3:195792428 - |
- | 0.0001 | 0.0635 | - | |
| 376_THR | ASN |
8.3kJPN chr3:195792385 rs760283092 |
- | 0.0005 | 0.0879 | - | |
| 379_ASN | SER |
gnomAD chr3:195792376 rs539830157 |
- | 0.000184735 | 0.1922 | - | |
| 407_ALA | THR |
gnomAD chr3:195791279 rs184956956 |
- | 0.00030189 | 0.4368 | - | |
| 420_GLY | SER |
VAR_051807
rs41295879 |
LB/B | - | 0.0561 | - | |
| 420_GLY | SER |
gnomAD chr3:195791240 rs41295879 |
- | 0.00236663 | 0.0561 | - | |
| 495_LYS | ARG |
8.3kJPN chr3:195787103 rs765448251 |
- | 0.0002 | 0.0803 | - | |
| 564_PRO | SER |
gnomAD chr3:195782160 rs571673598 |
- | 0.000182924 | 0.1465 | - | |
| 569_THR | SER |
8.3kJPN chr3:195782144 rs757696465 |
- | 0.0001 | 0.0787 | - | |
| 588_ARG | GLN |
8.3kJPN chr3:195782087 rs754713292 |
- | 0.0012 | 0.0938 | - | |
| 598_VAL | MET |
gnomAD chr3:195782058 rs144131234 |
- | 0.00010736 | 0.1118 | - | |
| 651_ARG | HIS |
8.3kJPN chr3:195780377 - |
- | 0.0001 | 0.7033 | - | |
| 669_PHE | TYR |
8.3kJPN chr3:195780323 - |
- | 0.0001 | 0.0935 | - | |
| 677_ARG | HIS |
VAR_051808
rs41298067 |
LB/B | - | 0.3205 | - | |
| 679_MET | LYS |
8.3kJPN chr3:195780293 - |
- | 0.0001 | 0.4001 | - | |
| 693_LYS | ARG |
8.3kJPN chr3:195779018 rs770731307 |
- | 0.0001 | 0.0591 | - | |
| 696_PRO | ARG |
8.3kJPN chr3:195779009 - |
- | 0.0001 | 0.557 | - | |
| 706_SER | PRO |
8.3kJPN chr3:195778980 - |
- | 0.0001 | 0.0691 | - | |
| 719_ARG | CYS |
8.3kJPN chr3:195778941 rs764730449 |
- | 0.0005 | 0.2132 | - | |
| 729_THR | MET |
gnomAD chr3:195778910 rs202242239 |
- | 0.000250523 | 0.1134 | - | |
| 729_THR | MET |
8.3kJPN chr3:195778910 rs202242239 |
- | 0.0005 | 0.1134 | - | |
| 753_VAL | ILE |
gnomAD chr3:195778839 rs141165322 |
- | 0.000206815 | 0.0637 | - |