| PDB ID | 1BBN
|
CHAIN | A |
|---|---|---|---|
| Protein name | INTERLEUKIN-4 | ||
| Uniprot Accession | P05112 | ||
| The number of similar proteins | 29 | ||
| The number of binding states | 7 | ||
| The number of binding partners | 6 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1BBN (CHAIN: A) | |
| 1 | Monomeric state |
| 2 |
4YDY
|
| 3 |
P24394
|
| 4 |
P31785
|
| 5 |
P24394
P31785
|
| 6 |
P78552
P24394
|
| 7 |
5FHX
5FHX
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 7_CYS | ARG |
VAR_020392
rs4986964 |
LB/B | - | 0.2119 | - | |
| 31_LEU | TRP |
8.3kJPN chr5:132010167 - |
- | 0.0001 | 0.271 | - | |
| 33_VAL | ILE |
gnomAD chr5:132010172 rs56279116 |
- | 0.000433444 | 0.0726 | - | |
| 33_VAL | ILE |
8.3kJPN chr5:132010172 rs56279116 |
- | 0.0246 | 0.0726 | - | |
| 68_ARG | CYS |
8.3kJPN chr5:132015484 rs757168472 |
- | 0.0001 | 0.1059 | - | |
| 68_ARG | HIS |
8.3kJPN chr5:132015485 rs781148776 |
- | 0.0003 | 0.0724 | - | |
| 72_ALA | GLU |
8.3kJPN chr5:132015497 rs779912651 |
- | 0.0001 | 0.1536 | - | |
| 95_TRP | ARG |
8.3kJPN chr5:132015565 - |
- | 0.0001 | 0.1409 | - | |
| 122_THR | MET |
8.3kJPN chr5:132018242 rs145068648 |
- | 0.0001 | 0.0663 | - |