PDB ID 1BBN     CHAIN A
Protein name INTERLEUKIN-4
Uniprot Accession P05112
The number of similar proteins 29
The number of binding states 7
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1BBN (CHAIN: A)
1 Monomeric state
2 4YDY  
3 P24394  
4 P31785  
5 P24394   P31785  
6 P78552   P24394  
7 5FHX   5FHX  

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Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   EAEAHKCDIT   LQEIIKTLNS   LTEQKTLCTE   LTVTDIFAAS   KDTTEKETFC   50
51   RAATVLRQFY   SHHEKDTRCL   GATAQQFHRH   KQLIRFLKRL   DRNLWGLAGL   100
101   NSCPVKEADQ   STLENFLERL   KTIMREKYSK   CSS     150

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
7_CYS ARG VAR_020392 rs4986964
LB/B - -
31_LEU TRP 8.3kJPN
chr5:132010167 		-
- 0.0001 -
33_VAL ILE gnomAD
chr5:132010172 		rs56279116
- 0.000433444 -
33_VAL ILE 8.3kJPN
chr5:132010172 		rs56279116
- 0.0246 -
68_ARG CYS 8.3kJPN
chr5:132015484 		rs757168472
- 0.0001 -
68_ARG HIS 8.3kJPN
chr5:132015485 		rs781148776
- 0.0003 -
72_ALA GLU 8.3kJPN
chr5:132015497 		rs779912651
- 0.0001 -
95_TRP ARG 8.3kJPN
chr5:132015565 		-
- 0.0001 -
122_THR MET 8.3kJPN
chr5:132018242 		rs145068648
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.