| PDB ID | 1ARL
|
CHAIN | A |
|---|---|---|---|
| Protein name | APO-CARBOXYPEPTIDASE A=ALPHA= (COX) | ||
| Uniprot Accession | P00730 | ||
| The number of similar proteins | 39 | ||
| The number of binding states | 7 | ||
| The number of binding partners | 6 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1ARL (CHAIN: A) | |
| 1 | Monomeric state |
| 2 |
58374130
|
| 3 |
P00730
|
| 4 |
P01075
|
| 5 |
P00730
P00730
|
| 6 |
1PYT
P00730
|
| 7 |
P00730
P81511
P81511
|
Downdload
Molecule viewer
|
Only interaction residues |
|
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|
Sequence information
|
Variants
| Residue | AA | Source | dbSNP | Clinical Significance |
Allele Frequency (> 0.0001) |
Disease name | |
|---|---|---|---|---|---|---|---|
| 5_ASP | ASN |
8.3kJPN chr7:130021666 |
rs782573440
|
- | 0.0008 | - | |
| 14_THR | ILE |
gnomAD chr7:130021694 |
rs150653308
|
- | 0.00186315 | - | |
| 27_ALA | GLY |
gnomAD chr7:130021977 |
rs183429188
|
- | 0.000183007 | - | |
| 27_ALA | GLY |
8.3kJPN chr7:130021977 |
rs183429188
|
- | 0.0024 | - | |
| 30_PRO | ARG |
8.3kJPN chr7:130021986 |
-
|
- | 0.0005 | - | |
| 54_THR | MET |
8.3kJPN chr7:130023239 |
rs781903028
|
- | 0.0001 | - | |
| 56_GLY | ASP |
gnomAD chr7:130023245 |
rs144546424
|
- | 0.00171453 | - | |
| 59_ARG | HIS |
gnomAD chr7:130023254 |
rs114365673
|
- | 0.000334648 | - | |
| 59_ARG | HIS |
8.3kJPN chr7:130023254 |
rs114365673
|
- | 0.0001 | - | |
| 71_ARG | GLN |
8.3kJPN chr7:130023290 |
rs377042960
|
- | 0.0001 | - | |
| 92_GLN | LYS |
gnomAD chr7:130023543 |
rs61735962
|
- | 0.0011059 | - | |
| 98_ALA | THR |
gnomAD chr7:130023561 |
rs34474469
|
- | 0.0260035 | - | |
| 110_VAL | ILE |
8.3kJPN chr7:130023597 |
-
|
- | 0.0002 | - | |
| 146_ASN | LYS |
ClinVar chr7:130024448 |
rs1796449608
|
Likely pathogenic | - | not provided [MedGen:C3661900] | |
| 159_ASN | LYS |
8.3kJPN chr7:130025006 |
rs782284797
|
- | 0.0001 | - | |
| 160_PRO | LEU |
8.3kJPN chr7:130025008 |
-
|
- | 0.0001 | - | |
| 172_SER | PRO |
ClinVar chr7:130025043 |
-
|
Likely pathogenic | - | not provided [MedGen:C3661900] | |
| 231_ALA | THR |
gnomAD chr7:130025713 |
rs77792157
|
- | 0.000183034 | - | |
| 231_ALA | THR |
8.3kJPN chr7:130025713 |
rs77792157
|
- | 0.0569 | - | |
| 252_GLY | GLU |
ClinVar chr7:130027677 |
rs2117509052
|
Likely pathogenic | - | not provided [MedGen:C3661900] | |
| 255_ILE | THR |
8.3kJPN chr7:130027686 |
-
|
- | 0.0001 | - | |
| 272_ARG | GLN |
8.3kJPN chr7:130027737 |
rs782284762
|
- | 0.0001 | - | |
| 276_ARG | CYS |
gnomAD chr7:130027748 |
rs201750163
|
- | 0.000131252 | - | |
| 276_ARG | CYS |
8.3kJPN chr7:130027748 |
rs201750163
|
- | 0.0001 | - | |
| 293_THR | MET |
8.3kJPN chr7:130027800 |
rs141400125
|
- | 0.0001 | - |