| PDB ID | 1AQ1
|
CHAIN | A |
|---|---|---|---|
| Protein name | CYCLIN-DEPENDENT PROTEIN KINASE 2 | ||
| Uniprot Accession | P24941 | ||
| The number of similar proteins | 456 | ||
| The number of binding states | 12 | ||
| The number of binding partners | 10 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1AQ1 (CHAIN: A) | |
| 1 | Monomeric state |
| 2 |
P61024
|
| 3 |
P89883
|
| 4 |
P20248
|
| 5 |
Q5MJ70
|
| 6 |
Q16667
|
| 7 |
Q5MJ70
P46527
|
| 8 |
P20248
P46527
|
| 9 |
P20248
Q99741
|
| 10 |
O94901
Q5MJ70
|
| 11 |
P24941
P20248
|
| 12 |
P24941
P20248
P20248
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 3_ASN | LYS |
gnomAD chr12:56360801 rs139342756 |
- | 0.000510365 | 0.4086 | - | |
| 15_TYR | SER |
VAR_016157
rs3087335 |
LB/B | - | 0.9846 | - | |
| 18_VAL | LEU |
VAR_053927
rs11554376 |
LB/B | - | 0.999 | - | |
| 45_PRO | LEU |
VAR_041972
- |
US | - | 0.997 | A glioblastoma multiforme sample | |
| 77_TYR | HIS |
8.3kJPN chr12:56361867 rs1325392225 |
- | 0.0001 | 0.899 | - | |
| 109_PHE | LEU |
8.3kJPN chr12:56362573 rs756703184 |
- | 0.0006 | 0.902 | - | |
| 200_ARG | GLN |
8.3kJPN chr12:56364838 rs763512696 |
- | 0.0001 | 0.3268 | - | |
| 210_ASP | ALA |
8.3kJPN chr12:56364868 - |
- | 0.0001 | 0.9891 | - | |
| 214_ARG | GLN |
8.3kJPN chr12:56364880 - |
- | 0.0001 | 0.7827 | - | |
| 231_THR | ASN |
8.3kJPN chr12:56364931 - |
- | 0.0001 | 0.2198 | - | |
| 245_ARG | GLN |
gnomAD chr12:56364973 rs144092294 |
- | 0.000222668 | 0.1034 | - | |
| 245_ARG | TRP |
8.3kJPN chr12:56364972 rs868674487 |
- | 0.0002 | 0.307 | - | |
| 245_ARG | GLN |
8.3kJPN chr12:56364973 rs144092294 |
- | 0.0019 | 0.1034 | - | |
| 255_LEU | VAL |
8.3kJPN chr12:56365002 rs1359177454 |
- | 0.0003 | 0.2584 | - | |
| 256_ASP | ASN |
8.3kJPN chr12:56365005 - |
- | 0.0001 | 0.1211 | - | |
| 260_ARG | GLN |
8.3kJPN chr12:56365018 rs774683147 |
- | 0.0001 | 0.0965 | - | |
| 270_ASP | ASN |
8.3kJPN chr12:56365320 rs759820038 |
- | 0.0001 | 0.3629 | - | |
| 290_THR | SER |
VAR_019988
rs2069413 |
LB/B | - | 0.0728 | - | |
| 290_THR | SER |
gnomAD chr12:56365381 rs2069413 |
- | 0.00232636 | 0.0728 | - | |
| 290_THR | SER |
8.3kJPN chr12:56365381 rs2069413 |
- | 0.0069 | 0.0728 | - |