PDB ID 1AJ5     CHAIN A
Protein name CALPAIN
Uniprot Accession Q64537
The number of similar proteins 39
The number of binding states 6
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1AJ5 (CHAIN: A)
1 Monomeric state
2 Q07009  
3 Q64537  
4 P27321   Q07009  
5 P04632   A0A376T1I0   A0A376T1I0  
6 P04632   P04632   A0A376T1I0   A0A376T1I0   A0A376T1I0  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  3
  2
  1
  0

Sequence information

1   EEERQFRKLF   VQLAGDDMEV   SATELMNILN   KVVTRHPDLK   TDGFGIDTCR   50
51   SMVAVMDSDT   TGKLGFEEFK   YLWNNIKKWQ   GIYKRFDTDR   SGTIGSNELP   100
101   GAFEAAGFHL   NQHIYSMIIR   RYSDETGNMD   FDNFISCLVR   LDAMFRAFRS   150
151   LDKNGTGQIQ   VNIQEWLQLT   MYS       200

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
119_ALA THR 8.3kJPN
chr19:36633826
rs1373988909
- 0.0004 - -
145_THR ILE 8.3kJPN
chr19:36634002
-
- 0.0001 - -
167_LYS ARG 8.3kJPN
chr19:36636745
-
- 0.0003 - -
179_ILE VAL 8.3kJPN
chr19:36636881
rs1368794322
- 0.0001 - -
184_ASP HIS 8.3kJPN
chr19:36636896
-
- 0.0001 - -
239_ASP GLY 8.3kJPN
chr19:36637203
-
- 0.0001 - -
258_VAL MET 8.3kJPN
chr19:36640524
-
- 0.0004 - -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.