PDB ID 1A7X     CHAIN A
Protein name FKBP12
Uniprot Accession P62942
The number of similar proteins 73
The number of binding states 6
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1A7X (CHAIN: A)
1 P62942  
2 Monomeric state
3 O00238  
4 P42345  
5 Q9BV73   Q9BV73  
6 P63099   P48452  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  5
  4
  3
  2
  1
  0

Sequence information

1   GVQVETISPG   DGRTFPKRGQ   TCVVHYTGML   EDGKKFDSSR   DRNKPFKFML   50
51   GKQEVIRGWE   EGVAQMSVGQ   RAKLTISPDY   AYGATGHPGI   IPPHATLVFD   100
101   VELLKLE           150

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
30_LEU PHE 8.3kJPN
chr2:24283689
-
- 0.0001 0.4441 -
37_ASP HIS 8.3kJPN
chr2:24283710
-
- 0.0001 0.9831 -
55_VAL MET 8.3kJPN
chr20:1356167
-
- 0.0001 0.9412 -
98_VAL ILE gnomAD
chr20:1352788
rs146341033
- 0.00126056 0.0688 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.