PDB ID 1A37     CHAIN A
Protein name 14-3-3 PROTEIN ZETA
Uniprot Accession P63103
The number of similar proteins 115
The number of binding states 11
The number of binding partners 9

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
1A37 (CHAIN: A)
1 P63104  
2 Monomeric state
3 P13612  
4 P63104   Q02156  
5 P63101   Q9R1V6  
6 P63104   P15056  
7 P63104   P04049  
8 P63104   P04150  
9 P63104   P30307  
10 P63104   Q29495   Q29495  
11 P63104   P15056   P15056  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   MDKNELVQKA   KLAEQAERYD   DMAACMKSVT   EQGAELSNEE   RNLLSVAYKN   50
51   VVGARRSSWR   VVSSIEQKTE   GAEKKQQMAR   EYREKIETEL   RDICNDVLSL   100
101   LEKFLIPNAS   QAESKVFYLK   MKGDYYRYLA   EVAAGDDKKG   IVDQSQQAYQ   150
151   EAFEISKKEM   QPTHPIRLGL   ALNFSVFYYE   ILNSPEKACS   LAKTAFDEAI   200
201   AELDTLSEES   YKDSTLIMQL   LRDNLTLWTS   DTQGDEAEAG   EGGEN   250

Variants

Residue AA Source /
dbSNP		 Clinical
Significance
 Allele
Frequency
(> 0.0001)		 AlphaMissense
pathogenicity		 Disease name
75_LYS GLN gnomAD
chr20:43530403
rs142757633
- 0.00180995 - -
75_LYS GLN 8.3kJPN
chr20:43530403
rs142757633
- 0.0003 - -
95_ASN SER 8.3kJPN
chr20:43530464
rs749944173
- 0.0001 - -
108_ASN SER gnomAD
chr20:43532662
rs151038182
- 0.000869624 - -
108_ASN SER 8.3kJPN
chr8:101937239
rs544713098
- 0.0001 - -
134_ALA VAL 8.3kJPN
chr8:101937161
-
- 0.0001 - -
143_ASP HIS 8.3kJPN
chr8:101936518
-
- 0.0001 - -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.