| PDB ID | 1A37
|
CHAIN | A |
|---|---|---|---|
| Protein name | 14-3-3 PROTEIN ZETA | ||
| Uniprot Accession | P63103 | ||
| The number of similar proteins | 127 | ||
| The number of binding states | 12 | ||
| The number of binding partners | 10 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 1A37 (CHAIN: A) | |
| 1 |
P63104
|
| 2 | Monomeric state |
| 3 |
P13612
|
| 4 |
P63104
Q02156
|
| 5 |
P63101
Q9R1V6
|
| 6 |
P63104
P15056
|
| 7 |
P63104
P10636
|
| 8 |
P63104
P04049
|
| 9 |
P63104
P04150
|
| 10 |
P63104
P30307
|
| 11 |
P63104
Q29495
Q29495
|
| 12 |
P63104
P15056
P15056
|
Downdload
Molecule viewer
|
Only interaction residues |
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Sequence information
|
Variants
| Residue | AA | Source / dbSNP |
Clinical Significance |
Allele Frequency (> 0.0001) |
AlphaMissense pathogenicity |
Disease name | |
|---|---|---|---|---|---|---|---|
| 14_GLU | TER |
ClinVar chr8:101961078 rs775309705 |
Pathogenic | - | - | Popov-Chang syndrome [MONDO:MONDO:0979865,MedGen:CN380660,OMIM:618428] | |
| 49_LYS | ASN |
ClinVar chr8:101960971 - |
Pathogenic | - | - | Popov-Chang syndrome [MONDO:MONDO:0979865,MedGen:CN380660,OMIM:618428] | |
| 75_LYS | GLN |
gnomAD chr20:43530403 rs142757633 |
- | 0.00180995 | - | - | |
| 75_LYS | GLN |
8.3kJPN chr20:43530403 rs142757633 |
- | 0.0003 | - | - | |
| 95_ASN | SER |
8.3kJPN chr20:43530464 rs749944173 |
- | 0.0001 | - | - | |
| 108_ASN | SER |
gnomAD chr20:43532662 rs151038182 |
- | 0.000869624 | - | - | |
| 108_ASN | SER |
8.3kJPN chr8:101937239 rs544713098 |
- | 0.0001 | - | - | |
| 127_ARG | CYS |
ClinVar chr8:101937183 - |
Pathogenic | - | - | not provided [MedGen:C3661900] | |
| 134_ALA | VAL |
8.3kJPN chr8:101937161 - |
- | 0.0001 | - | - | |
| 143_ASP | HIS |
8.3kJPN chr8:101936518 - |
- | 0.0001 | - | - | |
| 145_SER | LEU |
ClinVar chr8:101936511 rs754522887 |
Pathogenic | - | - | Popov-Chang syndrome [MONDO:MONDO:0979865,MedGen:CN380660,OMIM:618428] |