PDB ID 2B5L     CHAIN A
Protein name damage-specific DNA binding protein 1
GenBank ID 13435359
The number of similar proteins 32
The number of binding states 7
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state
Binding partners
2B5L (CHAIN: A)
1 P11207  
2 Monomeric state
3 Q92466  
4 Q96SW2  
5 Q9Y4B6  
6 Q13216  
7 Q13619   P11207  

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Format:

Molecule viewer

#binding
partners
  5
  4
  3
  2
  1
  0

Sequence information

1   MSYNYVVTAQ   KPTAVNGCVT   GHFTSAEDLN   LLIAKNTRLE   IYVVTAEGLR   50
51   PVKEVGMYGK   IAVMELFRPK   GESKDLLFIL   TAKYNACILE   YKQSGESIDI   100
101   ITRAHGNVQD   RIGRPSETGI   IGIIDPECRM   IGLRLYDGLF   KVIPLDRDNK   150
151   ELKAFNIRLE   ELHVIDVKFL   YGCQAPTICF   VYQDPQGRHV   KTYEVSLREK   200
201   EFNKGPWKQE   NVEAEASMVI   AVPEPFGGAI   IIGQESITYH   NGDKYLAIAP   250
251   PIIKQSTIVC   HNRVDPNGSR   YLLGDMEGRL   FMLLLEKEEQ   MDGTVTLKDL   300
301   RVELLGETSI   AECLTYLDNG   VVFVGSRLGD   SQLVKLNVDS   NEQGSYVVAM   350
351   ETFTNLGPIV   DMCVVDLERQ   GQGQLVTCSG   AFKEGSLRII   RNGIGIHEHA   400
401   SIDLPGIKGL   WPLRSDPNRE   TYDTLVLSFV   GQTRVLMLNG   EEVEETELMG   450
451   FVDDQQTFFC   GNVAHQQLIQ   ITSASVRLVS   QEPKALVSEW   KEPQAKNISV   500
501   ASCNSSQVVV   AVGRALYYLQ   IHPQELRQIS   HTEMEHEVAC   LDITPLGDSN   550
551   GLSPLCAIGL   WTDISARILK   LPSFELLHKE   MLGGEIIPRS   ILMTTFESSH   600
601   YLLCALGDGA   LFYFGLNIET   GLLSDRKKVT   LGTQPTVLRT   FRSLSTTNVF   650
651   ACSDRPTVIY   SSNHKLVFSN   VNLKEVNYMC   PLNSDGYPDS   LALANNSTLT   700
701   IGTIDEIQKL   HIRTVPLYES   PRKICYQEVS   QCFGVLSSRI   EVQDTSGGTT   750
751   ALRPSASTQA   LSSSVSSSKL   FSSSTAPHET   SFGEEVEVHN   LLIIDQHTFE   800
801   VLHAHQFLQN   EYALSLVSCK   LGKDPNTYFI   VGTAMVYPEE   AEPKQGRIVV   850
851   FQYSDGKLQT   VAEKEVKGAV   YSMVEFNGKL   LASINSTVRL   YEWTTEKDVR   900
901   TECNHYNNIM   ALYLKTKGDF   ILVGDLMRSV   LLLAYKPMEG   NFEEIARDFN   950
951   PNWMSAVEIL   DDDNFLGAEN   AFNLFVCQKD   SAATTDEERQ   HLQEVGLFHL   1000
1001   GEFVNVFCHG   SLVMQNLGET   STPTQGSVLF   GTVNGMIGLV   TSLSESWYNL   1050
1051   LLDMQNRLNK   VIKSVGKIEH   SFWRSFHTER   KTEPATGFID   GDLIESFLDI   1100
1101   SRPKMQEVVA   NLQYDDGSGM   KREATADDLI   KVVEELTRIH     1150

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(4.7kJPN)
Disease name
18_CYS GLY 4.7kJPN
chr11:61100389
-
- 0.0001 -
25_SER ALA 4.7kJPN
chr11:61099152
-
- 0.0001 -
40_GLU ASP 4.7kJPN
chr11:61099105
-
- 0.0001 -
157_ILE ASN 4.7kJPN
chr11:61096914
-
- 0.0001 -
163_HIS GLN 4.7kJPN
chr11:61096895
-
- 0.0001 -
241_ASN SER 4.7kJPN
chr11:61093123
rs1169556093
- 0.0001 -
252_ILE VAL 4.7kJPN
chr11:61093091
rs1200909412
- 0.0003 -
340_SER ILE 4.7kJPN
chr11:61089871
-
- 0.0001 -
419_ARG LEU 4.7kJPN
chr11:61084009
rs553181699
- 0.0014 -
517_TYR CYS 4.7kJPN
chr11:61081819
rs56006697
- 0.0009 -
527_ARG TRP 4.7kJPN
chr11:61081790
-
- 0.0001 -
626_ARG HIS 4.7kJPN
chr11:61081163
rs767530118
- 0.0001 -
626_ARG CYS 4.7kJPN
chr11:61081164
rs1302192657
- 0.0001 -
642_ARG HIS 4.7kJPN
chr11:61081115
rs376616995
- 0.0001 -
649_VAL ILE 4.7kJPN
chr11:61081095
rs1194687578
- 0.0002 -
781_SER ALA 4.7kJPN
chr11:61077827
-
- 0.0002 -
859_GLN ARG 4.7kJPN
chr11:61076540
-
- 0.0001 -
971_ALA GLY 4.7kJPN
chr11:61070548
-
- 0.0002 -
1022_THR SER 4.7kJPN
chr11:61070101
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.